Sökning: onr:"swepub:oai:DiVA.org:umu-222419" > International poole...
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001 | oai:DiVA.org:umu-222419 | |
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024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2224192 URI |
024 | 7 | a https://doi.org/10.1200/JCO.23.011012 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:2380796012 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1583156272 URI |
040 | a (SwePub)umud (SwePub)kid (SwePub)ki | |
041 | a engb eng | |
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100 | 1 | a Timmins, Iain R.u Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; Statistical Innovation, AstraZeneca, Cambridge, United Kingdom4 aut |
245 | 1 0 | a International pooled analysis of leisure-time physical activity and premenopausal breast cancer in women from 19 cohorts |
264 | 1 | b American Society of Clinical Oncology,c 2024 |
338 | a print2 rdacarrier | |
520 | a PURPOSE: There is strong evidence that leisure-time physical activity is protective against postmenopausal breast cancer risk but the association with premenopausal breast cancer is less clear. The purpose of this study was to examine the association of physical activity with the risk of developing premenopausal breast cancer.METHODS: We pooled individual-level data on self-reported leisure-time physical activity across 19 cohort studies comprising 547,601 premenopausal women, with 10,231 incident cases of breast cancer. Multivariable Cox regression was used to estimate hazard ratios (HRs) and 95% CIs for associations of leisure-time physical activity with breast cancer incidence. HRs for high versus low levels of activity were based on a comparison of risk at the 90th versus 10th percentiles of activity. We assessed the linearity of the relationship and examined subtype-specific associations and effect modification across strata of breast cancer risk factors, including adiposity.RESULTS: Over a median 11.5 years of follow-up (IQR, 8.0-16.1 years), high versus low levels of leisure-time physical activity were associated with a 6% (HR, 0.94 [95% CI, 0.89 to 0.99]) and a 10% (HR, 0.90 [95% CI, 0.85 to 0.95]) reduction in breast cancer risk, before and after adjustment for BMI, respectively. Tests of nonlinearity suggested an approximately linear relationship (Pnonlinearity = .94). The inverse association was particularly strong for human epidermal growth factor receptor 2-enriched breast cancer (HR, 0.57 [95% CI, 0.39 to 0.84]; Phet = .07). Associations did not vary significantly across strata of breast cancer risk factors, including subgroups of adiposity.CONCLUSION: This large, pooled analysis of cohort studies adds to evidence that engagement in higher levels of leisure-time physical activity may lead to reduced premenopausal breast cancer risk. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
700 | 1 | a Jones, Michael E.u Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a O'Brien, Katie M.u Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States4 aut |
700 | 1 | a Adami, Hans-Olovu Karolinska Institutet4 aut |
700 | 1 | a Aune, Dagfinnu Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Nutrition, Oslo New University College, Oslo, Norway; Department of Research, Cancer Registry of Norway, Oslo, Norway4 aut |
700 | 1 | a Baglietto, Laurau Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy4 aut |
700 | 1 | a Bertrand, Kimberly A.u Slone Epidemiology Center at Boston University, MA, Boston, United States4 aut |
700 | 1 | a Brantley, Kristen D.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Chen, Yuu Division of Epidemiology, Department of Population Health, NYU Grossman School of Medicine, New York, NY4 aut |
700 | 1 | a Clague DeHart, Jessicau School of Community and Global Health, Claremont Graduate University, CA, Claremont, United States4 aut |
700 | 1 | a Clendenen, Tess V.u Division of Epidemiology, Department of Population Health, NYU Grossman School of Medicine, New York, NY4 aut |
700 | 1 | a Dossus, Laureu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut |
700 | 1 | a Eliassen, A Heatheru Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Fletcher, Oliviau Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Fournier, Agnèsu UVSQ, CESP, Gustave Roussy, Heredity, Cancer, INSERM, Paris-Saclay University, Paris-South University, Villejuif, France4 aut |
700 | 1 | a Håkansson, Niclasu Karolinska Institutet4 aut |
700 | 1 | a Hankinson, Susan E.u Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, MA, Amherst, United States4 aut |
700 | 1 | a Houlston, Richard S.u Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Joshu, Corinne E.u Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, Liberia4 aut |
700 | 1 | a Kirsh, Victoria A.u Ontario Institute for Cancer Research, ON, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, ON, Toronto, Canada4 aut |
700 | 1 | a Kitahara, Cari M.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, MD, Bethesda, Liberia4 aut |
700 | 1 | a Koh, Woon-Puayu Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore4 aut |
700 | 1 | a Linet, Martha S.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, MD, Bethesda, Liberia4 aut |
700 | 1 | a Park, Hannah Luiu Department of Pathology and Laboratory Medicine, Department of Epidemiology, UC Irvine School of Medicine, CA, Irvine, United States4 aut |
700 | 1 | a Lynch, Brigid M.u Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia; Physical Activity Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia4 aut |
700 | 1 | a May, Anne M.u Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands4 aut |
700 | 1 | a Mellemkjær, Leneu Danish Cancer Society Research Center, Copenhagen, Denmark4 aut |
700 | 1 | a Milne, Roger L.u Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia4 aut |
700 | 1 | a Palmer, Julie R.u Slone Epidemiology Center at Boston University, MA, Boston, United States4 aut |
700 | 1 | a Ricceri, Fulviou Department of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, Public Health, University of Turin, Turin, Italy; Unit of Epidemiology, Regional Health Service ASL TO3, Turin, Italy4 aut |
700 | 1 | a Rohan, Thomas E.u Albert Einstein College of Medicine, NY, Bronx, United States4 aut |
700 | 1 | a Ruddy, Kathryn J.u Department of Oncology, Mayo Clinic, MN, Rochester, United States4 aut |
700 | 1 | a Sánchez, Maria-Joseu Escuela Andaluza de Salud Pública (EASP), Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain4 aut |
700 | 1 | a Shu, Xiao-Ouu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, TN, Nashville, United States4 aut |
700 | 1 | a Smith-Byrne, Karlu Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom4 aut |
700 | 1 | a Steindorf, Karenu Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany4 aut |
700 | 1 | a Sund, Malinu Umeå universitet,Kirurgi,Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland4 aut0 (Swepub:umu)masu0021 |
700 | 1 | a Vachon, Celine M.u Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, MN, Rochester, United States4 aut |
700 | 1 | a Vatten, Lars J.u Department of Public Health and Nursing, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway4 aut |
700 | 1 | a Visvanathan, Kalau Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, Liberia4 aut |
700 | 1 | a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization, Lyon, France4 aut |
700 | 1 | a Willett, Walter C.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Wolk, Alicjau Karolinska Institutet4 aut |
700 | 1 | a Yuan, Jian-Minu Division of Cancer Control and Population Sciences, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, PA, Pittsburgh, United States; Department of Epidemiology, School of Public Health, University of Pittsburgh, PA, Pittsburgh, United States4 aut |
700 | 1 | a Zheng, Weiu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, TN, Nashville, United States4 aut |
700 | 1 | a Nichols, Hazel B.u Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, United States4 aut |
700 | 1 | a Sandler, Dale P.u Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States4 aut |
700 | 1 | a Swerdlow, Anthony J.u Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; Division of Breast Cancer Research, Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Schoemaker, Minouk J.u Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; Real World Solutions, Amsterdam, Netherlands4 aut |
710 | 2 | a Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; Statistical Innovation, AstraZeneca, Cambridge, United Kingdomb Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 org |
773 | 0 | t Journal of Clinical Oncologyd : American Society of Clinical Oncologyg 42:8, s. 927-939q 42:8<927-939x 0732-183Xx 1527-7755 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-222419 |
856 | 4 8 | u https://doi.org/10.1200/JCO.23.01101 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:238079601 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:158315627 |
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