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The innervation pat...
The innervation pattern of the human Achilles tendon : studies of the normal and tendinosis tendon with markers for general and sensory innervation
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- Bjur, Dennis, 1965- (författare)
- Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB),Anatomi,Idrottsmedicin,Neuropeptidgruppen
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- Alfredson, Håkan (författare)
- Umeå universitet,Idrottsmedicin
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- Forsgren, Sture (författare)
- Umeå universitet,Anatomi
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(creator_code:org_t)
- 2005-02-09
- 2005
- Engelska.
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Ingår i: Cell and Tissue Research. - Berlin / Heidelberg : Springer. - 0302-766X .- 1432-0878. ; 320:1, s. 201-206
- Relaterad länk:
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http://www.springerl...
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visa fler...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Pain-free normal Achilles tendons and chronic painful Achilles tendons were examined by the use of antibodies against a general nerve marker (protein gene-product 9.5, PGP9.5), sensory markers (substance P, SP; calcitonin gene-related peptide, CGRP), and immunohistochemistry. In the normal tendons, immunoreactions against PGP9.5 and against SP/CGRP were encountered in the paratendinous loose connective tissue, being confined to nerve fascicles and to nerve fibers located in the vicinity of blood vessels. To some extent, these immunoreactions also occurred in the tendon tissue proper. Immunoreaction against PGP9.5 and against SP/CGRP was also observed in the tendinosis samples and included immunoreactive nerve fibers that were intimately associated with small blood vessels. In conclusion, Mechanoreceptors (sensory corpuscles) were occasionally observed, nerve-related components are present in association with blood vessels in both the normal and the tendinosis tendon.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Achilles Tendon/blood supply/injuries/*innervation/*pathology/surgery
- Adult
- Antibodies/metabolism
- Biological Markers/*analysis
- Biopsy
- Calcitonin Gene-Related Peptide/metabolism
- Female
- Humans
- Male
- Middle Aged
- Substance P/metabolism
- Ubiquitin Thiolesterase/metabolism
- Orthopaedics
- Ortopedi
- anatomi
- Human Anatomy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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