Sökning: onr:"swepub:oai:DiVA.org:umu-32335" > Differential effect...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03476naa a2200505 4500 | |
001 | oai:DiVA.org:umu-32335 | |
003 | SwePub | |
008 | 100310s2009 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-323352 URI |
024 | 7 | a https://doi.org/10.1038/oby.2009.732 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Goedecke, Julia H4 aut |
245 | 1 0 | a Differential effects of abdominal adipose tissue distribution on insulin sensitivity in black and white South African women |
264 | c 2012-09-06 | |
264 | 1 | b Wiley,c 2009 |
338 | a print2 rdacarrier | |
520 | a Black South African women are more insulin resistant than BMI-matched white women. The objective of the study was to characterize the determinants of insulin sensitivity in black and white South African women matched for BMI. A total of 57 normal-weight (BMI 18-25 kg/m(2)) and obese (BMI > 30 kg/m(2)) black and white premenopausal South African women underwent the following measurements: body composition (dual-energy X-ray absorptiometry), body fat distribution (computerized tomography (CT)), insulin sensitivity (S(I), frequently sampled intravenous glucose tolerance test), dietary intake (food frequency questionnaire), physical activity (Global Physical Activity Questionnaire), and socioeconomic status (SES, demographic questionnaire). Black women were less insulin sensitive (4.4 +/- 0.8 vs. 9.5 +/- 0.8 and 3.0 +/- 0.8 vs. 6.0 +/- 0.8 x 10(-5)/min/(pmol/l), for normal-weight and obese women, respectively, P < 0.001), but had less visceral adipose tissue (VAT) (P = 0.051), more abdominal superficial subcutaneous adipose tissue (SAT) (P = 0.003), lower SES (P < 0.001), and higher dietary fat intake (P = 0.001) than white women matched for BMI. S(I) correlated with deep and superficial SAT in both black (R = -0.594, P = 0.002 and R = 0.495, P = 0.012) and white women (R = -0.554, P = 0.005 and R = -0.546, P = 0.004), but with VAT in white women only (R = -0.534, P = 0.005). In conclusion, body fat distribution is differentially associated with insulin sensitivity in black and white women. Therefore, the different abdominal fat depots may have varying metabolic consequences in women of different ethnic origins. | |
653 | a apoptosis | |
653 | a cisplatin | |
653 | a malignant pleural mesothelioma (MPM) | |
653 | a phase-contrast microscopy (PCM) | |
653 | a scanning electron microscopy (SEM) | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Levitt, Naomi S4 aut |
700 | 1 | a Lambert, Estelle V4 aut |
700 | 1 | a Utzschneider, Kristina M4 aut |
700 | 1 | a Faulenbach, Mirjam V4 aut |
700 | 1 | a Dave, Joel A4 aut |
700 | 1 | a West, Sacha4 aut |
700 | 1 | a Victor, Hendriena4 aut |
700 | 1 | a Evans, Julietu Umeå universitet,Medicin4 aut |
700 | 1 | a Olsson, Tommyu Umeå universitet,Medicin4 aut0 (Swepub:umu)tool0003 |
700 | 1 | a Walker, Brian R4 aut |
700 | 1 | a Seckl, Jonathan R4 aut |
700 | 1 | a Kahn, Steven E4 aut |
710 | 2 | a Umeå universitetb Medicin4 org |
773 | 0 | t Obesityd : Wileyg 17:8, s. 1506-1512q 17:8<1506-1512x 1930-7381x 1930-739X |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1038/oby.2009.73 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-32335 |
856 | 4 8 | u https://doi.org/10.1038/oby.2009.73 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Kopiera och spara länken för att återkomma till aktuell vy