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Biochemical and phy...
Biochemical and physiological responses in liver and muscle of rainbow trout after long-term exposure to propiconazole
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Li, Zhi-Hua (författare)
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Zlabek, Vladimir (författare)
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Li, Ping (författare)
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- Grabic, Roman (författare)
- Umeå universitet,Kemiska institutionen
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Velisek, Josef (författare)
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Machova, Jana (författare)
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Randak, Tomas (författare)
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(creator_code:org_t)
- Elsevier Inc, 2010
- 2010
- Engelska.
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Ingår i: Ecotoxicology and Environmental Safety. - : Elsevier Inc. - 0147-6513 .- 1090-2414. ; 73:6, s. 1391-1396
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In this study, the chronic toxic effects of PCZ, a triazole fungicide commonly present in surface and ground water, on morphological indices, ROS generation and RNA/DNA ratio in liver and white muscle of rainbow trout were investigated. Fish were exposed at sublethal concentrations of PCZ (0.2, 50 and 500mugL(-1)) for 7, 20 and 30d. Compared with the control, there were significant lower CF and HSI in fish exposed at the highest concentration of PCZ. ROS levels in both tissues increased significantly at higher PCZ concentrations (50 and 500mugL(-1)) after 20d and above, as well as in muscle of fish exposed at lowest PCZ concentration (0.2mugL(-1)) after 30d. The hepatic antioxidant enzymes (SOD and CAT) activities were induced significantly at higher concentrations (50, 500mugL(-1)) of PCZ after 20d and at 50mugL(-1) after 30d. Additional, hepatic SOD activity was significantly induced at 0.2mugL(-1) after 30d. Compared with the hepatic antioxidant enzymes activities in fish exposed to 50mugL(-1) of PCZ, there was a decreasing trend in those exposed to 500mugL(-1) after 30d exposure. However, both the antioxidant enzymes activities were significantly inhibited in muscle of fish exposed to 500mugL(-1) PCZ after 30d. Moreover there was significant lower RNA/DNA ratio in both tissues after long-term exposure to higher concentration of PCZ. In short, environmental concentrations of PCZ could not induce obvious impacts on fish, but long-term exposure to higher concentrations of CBZ could affect seriously the health status of fish.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Nyckelord
- fish
- residual fungicide
- oxidative stress
- condition factor
- hepatosomatic index
- RNA/DNA ratio
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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