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Weight change in la...
Weight change in later life and risk of death amongst the elderly : the European Prospective Investigation into Cancer and Nutrition-Elderly Network on Ageing and Health study
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Bamia, C (författare)
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Halkjaer, J (författare)
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Lagiou, P (författare)
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visa fler...
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Trichopoulos, D (författare)
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Tjønneland, A (författare)
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Berentzen, T L (författare)
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Overvad, K (författare)
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Clavel-Chapelon, F (författare)
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Boutron-Ruault, M-C (författare)
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Rohrmann, S (författare)
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Linseisen, J (författare)
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Steffen, A (författare)
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Boeing, H (författare)
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May, A M (författare)
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Peeters, P H (författare)
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Bas Bueno-de-Mesquita, H (författare)
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van den Berg, S W (författare)
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Dorronsoro, M (författare)
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Barricarte, A (författare)
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Rodriguez Suarez, L (författare)
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Navarro, C (författare)
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González, C A (författare)
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Boffetta, P (författare)
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Pala, V (författare)
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- Hallmans, Göran, 1947- (författare)
- Umeå universitet,Näringsforskning
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Trichopoulou, A (författare)
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(creator_code:org_t)
- 2010-01-28
- 2010
- Engelska.
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 268:2, s. 133-144
- Relaterad länk:
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- OBJECTIVE: Later life weight change and mortality amongst elders. DESIGN: Nested case-control study. SETTING: Six countries from the European Investigation into Cancer and nutrition-Elderly, Network on Ageing and Health. SUBJECTS: A total of 1712 deceased (cases) and 4942 alive (controls) were selected from 34,239 participants, > or = 60 years at enrolment (1992-2000) who were followed-up until March 2007. Annual weight change was estimated as the weight difference from recruitment to the most distant from-date-of-death re-assessment, divided by the respective time. OUTCOME MEASURES: Mortality in relation to weight change was examined using conditional logistic regression. RESULTS: Weight loss > 1 kg year(-1) was associated with statistically significant increased death risk (OR = 1.65; 95% CI: 1.41-1.92) compared to minimal weight change (+/-1 kg year(-1)). Weight gain > 1 kg year(-1) was also associated with increased risk of death (OR = 1.15; 95% CI: 0.98-1.37), but this was evident and statistically significant only amongst overweight/obese (OR = 1.55; 95% CI: 1.17-2.05). In analyses by time interval since weight re-assessment, the association of mortality with weight loss was stronger for the interval proximal (< 1 year) to death (OR = 3.10; 95% CI: 2.03-4.72). The association of mortality with weight gain was stronger at the interval of more than 3 years and statistically significant only amongst overweight/obese (OR = 1.58; 95% CI: 1.07-2.33). Similar patterns were observed regarding death from circulatory diseases and cancer. CONCLUSIONS: In elderly, stable body weight is a predictor of lower subsequent mortality. Weight loss is associated with increased mortality, particularly short-term, probably reflecting underlying nosology. Weight gain, especially amongst overweight/obese elders, is also associated with increased mortality, particularly longer term.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- body mass index
- mortality
- obesity
- weight gain
- weight loss
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Bamia, C
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Halkjaer, J
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Lagiou, P
-
Trichopoulos, D
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Tjønneland, A
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Berentzen, T L
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visa fler...
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Overvad, K
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Clavel-Chapelon, ...
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Boutron-Ruault, ...
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Rohrmann, S
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Linseisen, J
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Steffen, A
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Boeing, H
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May, A M
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Peeters, P H
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Bas Bueno-de-Mes ...
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van den Berg, S ...
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Dorronsoro, M
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Barricarte, A
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Rodriguez Suarez ...
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Navarro, C
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González, C A
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Boffetta, P
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Pala, V
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Hallmans, Göran, ...
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Trichopoulou, A
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visa färre...
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Umeå universitet