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Sökning: onr:"swepub:oai:DiVA.org:umu-50862" > Poor Folate Status ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003198naa a2200385 4500
001oai:DiVA.org:umu-50862
003SwePub
008111229s2011 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-508622 URI
0247 a https://doi.org/10.3945/jn.111.1442202 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Manger, Mari S.4 aut
2451 0a Poor Folate Status Predicts Persistent Diarrhea in 6-to 30-Month-Old North Indian Children
264 1a Bethesda :b American Society for Nutrition,c 2011
338 a print2 rdacarrier
520 a Poor micronutrient status is associated with diarrheal illness, but it is not known whether low folate and/or cobalamin status are independent risk factors for diarrhea. We measured the association between plasma folate and cobalamin and subsequent diarrheal morbidity in a prospective cohort study of 2296 children aged 6-30 mo in New Delhi, India. Plasma concentrations of folate, cobalamin, total homocysteine (tHcy), and methylmalonic acid were determined at baseline. Whether a child had diarrhea was recorded during weekly visits in a 4-mo zinc supplementation trial. Diarrhea episodes lasting <7, >= 7, and >= 14 d were classified as acute, prolonged, and persistent, respectively. There was a total of 4596 child periods with acute, 633 with prolonged, and 117 with persistent diarrhea during follow-up. Children with plasma folate concentrations in the lowest quartile had higher odds of persistent diarrhea than children in the other quartiles [adjusted OR = 1.77(95% CI = 1.14, 2.75); P = 0.01]. This effect differed between boys [adjusted OR = 2.51 (95% CI = 1.47, 4.28)] and girls [adjusted OR = 1.03 (95% CI = 0.53, 2.01); P-interaction = 0.030]. We found a small but significant association between high plasma tHcy concentration and acute diarrhea [adjusted OR = 1.14 (95% CI = 1.04, 1.24); P = 0.006]. Plasma cobalamin concentration was not a predictor of diarrheal morbidity. In conclusion, poor folate status was an independent predictor of persistent diarrhea in this population. J. Nutr. 141: 2226-2232, 2011.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
7001 a Taneja, Sunita4 aut
7001 a Strand, Tor A.4 aut
7001 a Ueland, Per M.4 aut
7001 a Refsum, Helga4 aut
7001 a Schneede, Jörnu Umeå universitet,Klinisk farmakologi4 aut0 (Swepub:umu)josc0012
7001 a Nygard, Ottar4 aut
7001 a Sommerfelt, Halvor4 aut
7001 a Bhandari, Nita4 aut
7102 a Umeå universitetb Klinisk farmakologi4 org
7730 t Journal of Nutritiond Bethesda : American Society for Nutritiong 141:12, s. 2226-2232q 141:12<2226-2232x 0022-3166x 1541-6100
8564 u https://academic.oup.com/jn/article-pdf/141/12/2226/23948441/2226.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-50862
8564 8u https://doi.org/10.3945/jn.111.144220

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