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Sökning: onr:"swepub:oai:DiVA.org:umu-83832" > Molecular Detection...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004151naa a2200481 4500
001oai:DiVA.org:umu-83832
003SwePub
008131209s2011 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-838322 URI
024a https://doi.org/10.1155/2011/8519462 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Broman, Tu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
2451 0a Molecular Detection of Persistent Francisella tularensis Subspecies holarctica in Natural Waters
264 1b Hindawi Publishing Corporation,c 2011
338 a electronic2 rdacarrier
520 a Tularemia, caused by the bacterium Francisella tularensis, where F. tularensis subspecies holarctica has long been the cause of endemic disease in parts of northern Sweden. Despite this, our understanding of the natural life-cycle of the organism is still limited. During three years, we collected surface water samples (n = 341) and sediment samples (n = 245) in two areas in Sweden with endemic tularemia. Real-time PCR screening demonstrated the presence of F. tularenis lpnA sequences in 108 (32%) and 48 (20%) of the samples, respectively. The 16S rRNA sequences from those samples all grouped to the species F. tularensis. Analysis of the FtM19InDel region of lpnA-positive samples from selected sampling points confirmed the presence of F. tularensis subspecies holarctica-specific sequences. These sequences were detected in water sampled during both outbreak and nonoutbreak years. Our results indicate that diverse F. tularensis-like organisms, including F. tularensis subsp. holarctica, persist in natural waters and sediments in the investigated areas with endemic tularemia.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Andra medicinska och farmaceutiska grundvetenskaper0 (SwePub)301992 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Other Basic Medicine0 (SwePub)301992 hsv//eng
653 a Clinical Bacteriology
653 a klinisk bakteriologi
700a Thelaus, J4 aut
700a Andersson, A-Cu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Bäckman, Su Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Wikström, Pu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Larsson, Eu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Granberg, Mu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Karlsson, Lu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
700a Bäck, Eu Department of Infectious Diseases, Örebro University Hospital, Örebro4 aut
700a Eliasson, Hu Department of Infectious Diseases, Örebro University Hospital, Örebro4 aut
700a Mattsson, Ru National Veterinary Institute, Uppsala4 aut
700a Sjöstedt, Anders,d 1957-u Umeå universitet,Klinisk bakteriologi,Arcum4 aut0 (Swepub:umu)ansj0004
700a Forsman, Mu Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeå4 aut
710a Department of CBRN Defence and Security, Swedish Defence Research Agency, Umeåb Department of Infectious Diseases, Örebro University Hospital, Örebro4 org
773t International Journal of Microbiologyd : Hindawi Publishing Corporationg 2011, s. Article ID 851946-q 2011<Article ID 851946-x 1687-918Xx 1687-9198
856u https://doi.org/10.1155/2011/851946y Fulltext
856u https://umu.diva-portal.org/smash/get/diva2:677405/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u http://downloads.hindawi.com/journals/ijmicro/2011/851946.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-83832
8564 8u https://doi.org/10.1155/2011/851946

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