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The Swedish Nationa...
The Swedish National Penile Cancer Register : Incidence, Tumour Characteristics, Management and Survival
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- Kirrander, Peter, 1978- (författare)
- Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Dept Urol, SE-70185 Orebro, Sweden.
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- Sherif, Amir (författare)
- Umeå universitet,Urologi och andrologi,Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umea, Sweden.
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- Friedrich, Bengt (författare)
- Umeå universitet,Urologi och andrologi,Umea Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umea, Sweden.
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- Lambe, Mats (författare)
- Karolinska Institutet,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.
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- Håkansson, Ulf (författare)
- Skane Univ, Dept Urol, Malmo, Sweden.
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(creator_code:org_t)
- 2015-05-04
- 2016
- Engelska.
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Ingår i: BJU International. - : John Wiley & Sons. - 1464-4096 .- 1464-410X. ; 117:2, s. 287-292
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: To assess penile cancer incidence, stage distribution, adherence to guidelines, and prognostic factors in a population-based setting.PATIENTS AND METHODS: The population-based Swedish National Penile Cancer Register (NPECR) contains detailed information on tumour characteristics and management patterns. ● A total of 1678 men with primary squamous cell carcinoma of the penis identified in the NPECR between 2000 and 2012 were included in the study. RESULTS: The mean age-adjusted incidence of penile cancer was 2.1/100,000 men, remaining virtually unchanged during the study period. At diagnosis, 14% and 2% were clinically N+ and M+, respectively. Most patients were staged pTis (34%), pT2 (19%), or pT1 (18%), whereas stage was unavailable in 18%. Organ-preserving treatment was used in 71% of Tis-T1 tumours. In cN0 and ≥pT1G2 patients, 50% underwent lymph node staging, while 74% of cN1-3 patients underwent lymph node dissection. The overall 5-year relative survival was 82%. Men aged ≥40 years and those with pT2-3, G2-3 and N+ tumours had worse outcome.CONCLUSION: The incidence of penile cancer in Sweden is stable. Most men presented with localised disease, and the proportion of non-invasive tumours was high. During the period under study, adherence to guidelines was suboptimal. The overall 5-year relative survival was 82%. Older age, increasing tumour stage and grade, and increasing lymph node stage were associated with poorer survival.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- penile cancer
- population-based
- incidence
- TNM
- prognostic factors
- survival
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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