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Sökning: onr:"swepub:oai:DiVA.org:umu-96595" > Weight change in mi...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005708naa a2201009 4500
001oai:DiVA.org:umu-96595
003SwePub
008141124s2014 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:98732c14-f299-4176-b60a-dd8eea283353
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-965952 URI
0247 a https://doi.org/10.1002/ijc.289262 DOI
0247 a https://lup.lub.lu.se/record/47839412 URI
040 a (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Emaus, Marleen J.4 aut
2451 0a Weight change in middle adulthood and breast cancer risk in the EPIC-PANACEA study
264 c 2014-05-16
264 1b Wiley,c 2014
338 a print2 rdacarrier
520 a Long-term weight gain (i.e., weight gain since age 20) has been related to higher risk of postmenopausal breast cancer, but a lower risk of premenopausal breast cancer. The effect of weight change in middle adulthood is unclear. We investigated the association between weight change in middle adulthood (i.e., women aged 40-50 years) and the risk of breast cancer before and after the age of 50. We included female participants of the European Prospective Investigation into Cancer and Nutrition cohort, with information on anthropometric measures at recruitment and after a median follow-up of 4.3 years. Annual weight change was categorized using quintiles taking quintile 2 and 3 as the reference category (-0.44 to 0.36 kg/year). Multivariable Cox proportional hazards regression analysis was used to examine the association. 205,723 women were included and 4,663 incident breast cancer cases were diagnosed during a median follow-up of 7.5 years (from second weight assessment onward). High weight gain (Q5: 0.83-4.98 kg/year) was related to a slightly, but significantly higher breast cancer risk (HRQ5_versus_Q2/3: 1.09, 95% CI: 1.01-1.18). The association was more pronounced for breast cancer diagnosed before or at age 50 (HRQ5_versus_Q2/3: 1.37, 95% CI: 1.02-1.85). Weight loss was not associated with breast cancer risk. There was no evidence for heterogeneity by hormone receptor status. In conclusion, high weight gain in middle adulthood increases the risk of breast cancer. The association seems to be more pronounced for breast cancer diagnosed before or at age 50. Our results illustrate the importance of avoiding weight gain in middle adulthood.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a breast cancer
653 a adult weight gain
653 a menopausal status
653 a estrogen receptor
653 a progesterone receptor
653 a breast cancer
653 a adult weight gain
653 a menopausal status
653 a estrogen receptor
653 a progesterone receptor
7001 a van Gils, Carla H.4 aut
7001 a Bakker, Marije F.4 aut
7001 a Bisschop, Charlotte N. Steins4 aut
7001 a Monninkhof, Evelyn M.4 aut
7001 a Bueno-de-Mesquita, H. B(as)4 aut
7001 a Travier, Noemie4 aut
7001 a Berentzen, Tina Landsvig4 aut
7001 a Overvad, Kim4 aut
7001 a Tjonneland, Anne4 aut
7001 a Romieu, Isabelle4 aut
7001 a Rinaldi, Sabina4 aut
7001 a Chajes, Veronique4 aut
7001 a Gunter, Marc J.4 aut
7001 a Clavel-Chapelon, Francoise4 aut
7001 a Fagherazzi, Guy4 aut
7001 a Mesrine, Sylvie4 aut
7001 a Chang-Claude, Jenny4 aut
7001 a Kaaks, Rudolf4 aut
7001 a Boeing, Heiner4 aut
7001 a Aleksandrova, Krasimira4 aut
7001 a Trichopoulou, Antonia4 aut
7001 a Naska, Androniki4 aut
7001 a Orfanos, Philippos4 aut
7001 a Palli, Domenico4 aut
7001 a Agnoli, Claudia4 aut
7001 a Tumino, Rosario4 aut
7001 a Vineis, Paolo4 aut
7001 a Mattiello, Amalia4 aut
7001 a Braaten, Tonje4 aut
7001 a Borch, Kristin Benjaminsen4 aut
7001 a Lund, Eiliv4 aut
7001 a Menendez, Virginia4 aut
7001 a Sanchez, Maria-Jose4 aut
7001 a Navarro, Carmen4 aut
7001 a Barricarte, Aurelio4 aut
7001 a Amiano, Pilar4 aut
7001 a Sund, Malin,d 1972-u Umeå universitet,Kirurgi4 aut0 (Swepub:umu)masu0021
7001 a Andersson, Anneu Umeå universitet,Onkologi4 aut0 (Swepub:umu)ankr0012
7001 a Borgquist, Signeu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ront-sbo
7001 a Olsson, Åsau Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)med-aol
7001 a Khaw, Kay-Tee4 aut
7001 a Wareham, Nick4 aut
7001 a Travis, Ruth C.4 aut
7001 a Riboli, Elio4 aut
7001 a Peeters, Petra H. M.4 aut
7001 a May, Anne M.4 aut
7102 a Umeå universitetb Kirurgi4 org
7730 t International Journal of Cancerd : Wileyg 135:12, s. 2887-2899q 135:12<2887-2899x 0020-7136x 1097-0215
8564 u http://dx.doi.org/10.1002/ijc.28926y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96595
8564 8u https://doi.org/10.1002/ijc.28926
8564 8u https://lup.lub.lu.se/record/4783941

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