Sökning: onr:"swepub:oai:DiVA.org:umu-99788" > Anal carcinoma - Su...
Fältnamn | Indikatorer | Metadata |
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000 | 04307naa a2200565 4500 | |
001 | oai:DiVA.org:umu-99788 | |
003 | SwePub | |
008 | 150212s2014 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:6390a24b-d036-4a01-a2ce-5e22509b71f5 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-997882 URI |
024 | 7 | a https://doi.org/10.1016/j.radonc.2014.10.0022 DOI |
024 | 7 | a https://lup.lub.lu.se/record/49084872 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Leon, Otiliau Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-ole |
245 | 1 0 | a Anal carcinoma - Survival and recurrence in a large cohort of patients treated according to Nordic guidelines |
264 | 1 | b Elsevier BV,c 2014 |
338 | a print2 rdacarrier | |
520 | a Objective:To evaluate treatment outcome in a large population-based cohort of patients with anal cancer treated according to Nordic guidelines.Material:Clinical data were collected on 1266 patients with anal squamous cell carcinoma diagnosed from 2000 to 2007 in Sweden, Norway and Denmark. 886 of the patients received radiotherapy 5464 Gy with or without chemotherapy (5-fluorouracil plus cisplatin or mitomycin). according to different protocols, stratified by tumor stage.Results:High age, male gender, large primary tumor, lymph node metastases, distant metastases, poor performance status, and non-inclusion into a protocol were all independent factors associated with worse outcome. Among patients treated according to any of the protocols, the 3-year recurrence-free survival ranged from 63% to 76%, with locoregional recurrences in 17% and distant metastases in 11% of patients. The highest rate of inguinal recurrence (11%) was seen in patients with small primary tumors, treated without inguinal irradiation.Conclusions:Good treatment efficacy was obtained with Nordic, widely implemented, guidelines for treatment of anal cancer. Inguinal prophylactic irradiation should be recommended also for small primary tumors. (C) 2014 Elsevier Ireland Ltd. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a Anal cancer | |
653 | a Radiotherapy | |
653 | a Chemoradiotherapy | |
700 | 1 | a Guren, Marianne4 aut |
700 | 1 | a Hagberg, Oskaru Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)mats-oha |
700 | 1 | a Glimelius, Bengt4 aut |
700 | 1 | a Dahl, Olav4 aut |
700 | 1 | a Havsteen, Hanne4 aut |
700 | 1 | a Naucler, Gisela4 aut |
700 | 1 | a Svensson, Christer4 aut |
700 | 1 | a Tveit, Kjell Magne4 aut |
700 | 1 | a Jakobsen, Anders4 aut |
700 | 1 | a Pfeiffer, Per4 aut |
700 | 1 | a Wanderas, Eva4 aut |
700 | 1 | a Ekman, Tor4 aut |
700 | 1 | a Lindh, Birgittau Umeå universitet,Institutionen för strålningsvetenskaper4 aut0 (Swepub:umu)bili0014 |
700 | 1 | a Balteskard, Lise4 aut |
700 | 1 | a Frykholm, Gunilla4 aut |
700 | 1 | a Johnsson, Andersu Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)onk-ajo |
710 | 2 | a Tumörmikromiljöb Sektion I4 org |
773 | 0 | t Radiotherapy and Oncologyd : Elsevier BVg 113:3, s. 352-358q 113:3<352-358x 0167-8140x 1879-0887 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/25499203?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1016/j.radonc.2014.10.002y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-99788 |
856 | 4 8 | u https://doi.org/10.1016/j.radonc.2014.10.002 |
856 | 4 8 | u https://lup.lub.lu.se/record/4908487 |
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