Sökning: onr:"swepub:oai:DiVA.org:uu-102945" >
Familial osteochond...
-
Stattin, Eva-Lena,1960-Umeå universitet,Medicinsk och klinisk genetik
(författare)
Familial osteochondritis dissecans associated with early osteoarthritis and disproportionate short stature
- Artikel/kapitelEngelska2008
Förlag, utgivningsår, omfång ...
-
London :Elsevier BV,2008
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:uu-102945
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-102945URI
-
https://doi.org/10.1016/j.joca.2007.11.009DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-4246URI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22382URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Validerad; 2008; 20080124 (andbra)
-
OBJECTIVE: Familial osteochondritis dissecans (OCD) is a rare disorder characterised by disturbed chondro-skeletal development, disproportionate growth and deformation of the skeleton. DESIGN: We identified a five-generation family with 15 living affected members from Northern Sweden. The disorder was diagnosed with a case definition of OCD in at least one joint. RESULTS: Main clinical findings consisted of OCD in knees and/or hips and/or elbows, disproportionate short stature and early osteoarthritis (OA). There were no radiological indications of epiphyseal dysplasia. Anthropometric measurements of affected individuals showed short stature, a high ratio between sitting height and total height, a relatively normal arm span and head circumference. In 12 of 15 cases, onset was during late childhood or adolescence and OA had developed in seven of those patients. CONCLUSIONS: Our observation suggests that OA is a frequent complication in familial OCD even though the lesions appear before closure of physis.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Tegner, YelvertonLuleå tekniska universitet,Medicinsk vetenskap,Department of Health Sciences, Luleå Technical University, Sweden(Swepub:ltu)yelteg
(författare)
-
Domellöf, MagnusUmeå universitet,Pediatrik(Swepub:umu)mado0002
(författare)
-
Dahl, NiklasUppsala universitet,Institutionen för genetik och patologi,Department of Genetics and Pathology, The Rudbeck Laboratory, Uppsala University, Sweden.(Swepub:uu)nikldahl
(författare)
-
Umeå universitetMedicinsk och klinisk genetik
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Osteoarthritis and CartilageLondon : Elsevier BV16:8, s. 890-61063-45841522-9653
Internetlänk
Hitta via bibliotek
Till lärosätets databas