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The monoamine oxida...
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Nilsson, Kent W.Uppsala universitet,Centrum för klinisk forskning, Västerås,Centre for Clinical Research, Uppsala University, Central Hospital Västerås, Västerås, Sweden
(författare)
The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption
- Artikel/kapitelEngelska2007
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Uppsala Univ, Cent Hosp Vasteras, Clin Res Ctr, Vasteras, Sweden. Uppsala Univ, Pharmacol Unit, Dept Neurosci, Uppsala, Sweden.Wiley,2007
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Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-11381
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-11381URI
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https://doi.org/10.1111/j.1360-0443.2006.01702.xDOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111358URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-52058URI
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Språk:engelska
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Sammanfattning på:engelska
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AIM: To investigate possible interactions between a polymorphism in the monoamine oxidase A (MAO-A) gene promoter, family relations and maltreatment/sexual abuse on adolescent alcohol-related problem behaviour among male adolescents. DESIGN, SETTING AND PARTICIPANTS: A cross-sectional study of a randomized sample of 66 male individuals from a total population of 16- and 19-year adolescents from a Swedish county. Boys, who volunteered to participate answering an alcohol-related problem/behaviour questionnaire, were investigated with regard to interactions between such problems, family function, maltreatment and MAO-A genotype. MEASUREMENTS: MAO-A genotype, family relations history, history of being maltreated or abused and alcohol-related problem behaviour. FINDINGS: Boys with the short (three-repeat) variant of the MAO-A gene, who had been maltreated/abused or came from families with poor relations, showed significantly higher scores of alcohol-related problems. We also found that maltreatment/abuse independently showed the strongest relation to alcohol-related problems among boys in our model. CONCLUSIONS: The results suggest that both maltreatment and MAO-A genotype may be useful for the understanding of male adolescent alcohol-related problem behaviour.
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Sjöberg, Rickard L.Uppsala universitet,Centrum för klinisk forskning, Västerås,Centre for Clinical Research, Uppsala University, Central Hospital Västerås, Västerås, Sweden(Swepub:uu)leiflind
(författare)
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Wargelius, Hanna-LinnUppsala universitet,Institutionen för neurovetenskap,Uppsala University, Uppsala, Sweden(Swepub:uu)hawar676
(författare)
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Leppert, JerzyUppsala universitet,Centrum för klinisk forskning, Västerås,Centre for Clinical Research, Uppsala University, Central Hospital Västerås, Västerås, Sweden(Swepub:uu)jelep103
(författare)
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Lindström, LeifUppsala universitet,Centrum för klinisk forskning, Västerås(Swepub:uu)leiflind
(författare)
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Oreland, LarsUppsala universitet,Institutionen för neurovetenskap,Uppsala universitet, Sweden(Swepub:uu)larsore
(författare)
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Uppsala universitetCentrum för klinisk forskning, Västerås
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:AddictionUppsala Univ, Cent Hosp Vasteras, Clin Res Ctr, Vasteras, Sweden. Uppsala Univ, Pharmacol Unit, Dept Neurosci, Uppsala, Sweden. : Wiley102:3, s. 389-3980965-21401360-0443
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