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The impact of birth...
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Eriksson, Margaretha,1951-Uppsala universitet,Allmänmedicin och klinisk epidemiologi
(författare)
The impact of birth weight on prostate cancer incidence and mortality in a population-based study of men born in 1913 and followed up from 50 to 85 years of age
- Artikel/kapitelEngelska2007
Förlag, utgivningsår, omfång ...
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2007
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Wiley,2007
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-13899
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-13899URI
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https://doi.org/10.1002/pros.20428DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:115753149URI
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https://gup.ub.gu.se/publication/43786URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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BACKGROUND: Insulin-like growth factor-I (IGF-I) hormone is directly associated with birth weight (BW), and high IGF-I measured in adults is associated with increased risk of prostate cancer (PCA). Whether BW and PCA are related is inconclusive to date. METHODS: BW and PCA incidence and mortality data for a population-based cohort of 1,436 singleton Swedish men born in 1913 and followed until 85 years of age were obtained. RESULTS: BW > or = 4,250 g was associated with significantly higher PCA incidence [62% (CI: 4%-151%)] and PCA mortality [82% (CI: 3%-221%)] than BW 3,001-4,249 g, even when other potential effect modifiers were taken into account. The hazards ratio for PCA incidence fell from approximately 3 at age 50 to unity at age 85. Approximately one out of every six PCA incident cases between 50 and 70 years of age could be attributed to BW > or = 4,250 g. CONCLUSIONS: In the current study PCA incidence and mortality rate appears to increase with BW.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Wedel, HansNordic School of Public Health, Gothenburg
(författare)
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Wallander, Mari-AnnUppsala universitet,Allmänmedicin och klinisk epidemiologi(Swepub:uu)marwa311
(författare)
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Krakau, IngvarKarolinska Institutet
(författare)
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Hugosson, Jonas,1955Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xhugjo
(författare)
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Carlsson, StureDepartment of Surgery, Kungälv Hospital
(författare)
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Svärdsudd, KurtUppsala universitet,Allmänmedicin och klinisk epidemiologi(Swepub:uu)kurtsvar
(författare)
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Uppsala universitetAllmänmedicin och klinisk epidemiologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:The Prostate: Wiley67:11, s. 1247-12540270-41371097-0045
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