Sökning: onr:"swepub:oai:DiVA.org:uu-207317" > Whole-genome sequen...
Fältnamn | Indikatorer | Metadata |
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000 | 02841naa a2200481 4500 | |
001 | oai:DiVA.org:uu-207317 | |
003 | SwePub | |
008 | 130912s2011 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2073172 URI |
024 | 7 | a https://doi.org/10.1038/ng.9112 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cao, Jun4 aut |
245 | 1 0 | a Whole-genome sequencing of multiple Arabidopsis thaliana populations. |
264 | c 2011-08-28 | |
264 | 1 | b Springer Science and Business Media LLC,c 2011 |
338 | a print2 rdacarrier | |
520 | a The plant Arabidopsis thaliana occurs naturally in many different habitats throughout Eurasia. As a foundation for identifying genetic variation contributing to adaptation to diverse environments, a 1001 Genomes Project to sequence geographically diverse A. thaliana strains has been initiated. Here we present the first phase of this project, based on population-scale sequencing of 80 strains drawn from eight regions throughout the species' native range. We describe the majority of common small-scale polymorphisms as well as many larger insertions and deletions in the A. thaliana pan-genome, their effects on gene function, and the patterns of local and global linkage among these variants. The action of processes other than spontaneous mutation is identified by comparing the spectrum of mutations that have accumulated since A. thaliana diverged from its closest relative 10 million years ago with the spectrum observed in the laboratory. Recent species-wide selective sweeps are rare, and potentially deleterious mutations are more common in marginal populations. | |
650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
700 | 1 | a Schneeberger, Korbinian4 aut |
700 | 1 | a Ossowski, Stephan4 aut |
700 | 1 | a Günther, Torsten4 aut |
700 | 1 | a Bender, Sebastian4 aut |
700 | 1 | a Fitz, Joffrey4 aut |
700 | 1 | a Koenig, Daniel4 aut |
700 | 1 | a Lanz, Christa4 aut |
700 | 1 | a Stegle, Oliver4 aut |
700 | 1 | a Lippert, Christoph4 aut |
700 | 1 | a Wang, Xi4 aut |
700 | 1 | a Ott, Felix4 aut |
700 | 1 | a Müller, Jonas4 aut |
700 | 1 | a Alonso-Blanco, Carlos4 aut |
700 | 1 | a Borgwardt, Karsten4 aut |
700 | 1 | a Schmid, Karl J4 aut |
700 | 1 | a Weigel, Detlef4 aut |
773 | 0 | t Nature geneticsd : Springer Science and Business Media LLCg 43:10, s. 956-63q 43:10<956-63x 1546-1718x 1061-4036 |
856 | 4 | u https://www.nature.com/articles/ng.911.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-207317 |
856 | 4 8 | u https://doi.org/10.1038/ng.911 |
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