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How kinetically acc...
How kinetically accessible is an RNA target for hybridization with an antisense oligo? A lesson from an RNA target which is as small as a 20mer
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- Puri, N (författare)
- Uppsala universitet
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- Chattopadhyaya, J (författare)
- Uppsala universitet
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(creator_code:org_t)
- PERGAMON-ELSEVIER SCIENCE LTD, 1999
- 1999
- Engelska.
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Ingår i: TETRAHEDRON. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0040-4020. ; 55:5, s. 1505-1516
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- A 20 mer RNA (1), characterized as a duplex with two A.A mismatch basepairs and four tandem G.U wobble basepairs, was targeted at the first A.A internal loop by nonameric 5'-Polyarene DNA-conjugates. For comparison, its DNA counterpart (10), which was fou
Nyckelord
- antisense target; polyarenes; DNA conjugates; NUCLEAR-MAGNETIC-RESONANCE; CIRCULAR-DICHROISM; MISMATCHES; DNA; STABILITY; SEQUENCE; NMR; OLIGONUCLEOTIDES; THERMODYNAMICS; TRANSITIONS
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