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Vital capacity and ...
Vital capacity and COPD : the Swedish CArdioPulmonary bioImage Study (SCAPIS)
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- Toren, Kjell (författare)
- University of Gothenburg
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- Olin, Anna-Carin (författare)
- University of Gothenburg
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- Lindberg, Anne (författare)
- Umeå universitet,Umeå University,Lungmedicin,Medicin
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- Vikgren, Jenny (författare)
- University of Gothenburg
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- Schioler, Linus (författare)
- University of Gothenburg
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- Brandberg, John (författare)
- University of Gothenburg
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- Johnsson, Ase (författare)
- University of Gothenburg
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- Engström, Gunnar (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
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- Persson, Lennart (författare)
- Linköping University,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Lungmedicinska kliniken US
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- Skold, Magnus (författare)
- Karolinska Institutet,Karolinska Institute
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- Hedner, Jan (författare)
- University of Gothenburg
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- Lindberg, Eva (författare)
- Uppsala universitet,Lungmedicin och allergologi,Uppsala University, Sweden
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- Malinovschi, Andrei (författare)
- Uppsala universitet,Klinisk fysiologi,Uppsala University, Sweden
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- Piitulainen, Eeva (författare)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine
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- Wollmer, Per (författare)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine
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- Rosengren, Annika (författare)
- University of Gothenburg
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- Janson, Christer (författare)
- Uppsala universitet,Lungmedicin och allergologi,Uppsala University, Sweden
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- Blomberg, Anders (författare)
- Umeå universitet,Umeå University,Lungmedicin,Medicin
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- Bergstrom, Goran (författare)
- University of Gothenburg
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(creator_code:org_t)
- DOVE MEDICAL PRESS LTD, 2016
- 2016
- Engelska.
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Ingår i: The International Journal of Chronic Obstructive Pulmonary Disease. - : DOVE MEDICAL PRESS LTD. - 1176-9106 .- 1178-2005. ; 11, s. 927-933
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https://liu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://doi.org/10.2...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.2...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value <0.7 or below the lower limit of normal (LLN). Forced vital capacity (FVC) is a proxy for VC. The first aim was to compare the use of FVC and VC, assessed as the highest value of FVC or slow vital capacity (SVC), when assessing the FEV1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were investigated with FEV1, FVC, and SVC after bronchodilation. Global Initiative for Chronic Obstructive Lung Disease (GOLD) COPDFVC was defined as FEV1/FVC <0.7, GOLDCOPD(VC) as FEV1/VC <0.7 using the maximum value of FVC or SVC, LLNCOPDFVC as FEV1/FVC below the LLN, and LLNCOPDVC as FEV1/VC below the LLN using the maximum value of FVC or SVC. Results: Prevalence of GOLDCOPD(FVC) was 10.0% (95% confidence interval [CI] 8.2-12.0) and the prevalence of LLNCOPDFVC was 9.5% (95% CI 7.8-11.4). When estimates were based on VC, the prevalence became higher; 16.4% (95% CI 14.3-18.9) and 15.6% (95% CI 13.5-17.9) for GOLDCOPD(VC) and LLNCOPDVC, respectively. The group of additional subjects classified as having COPD based on VC, had lower FEV1, more wheeze and higher residual volume compared to subjects without any COPD. Conclusion: The prevalence of COPD was significantly higher when the ratio FEV1/VC was calculated using the highest value of SVC or FVC compared with using FVC only. Subjects classified as having COPD when using the VC concept were more obstructive and with indications of air trapping. Hence, the use of only FVC when assessing airflow limitation may result in a considerable under diagnosis of subjects with mild COPD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- obstructive
- epidemiology
- general population
- air trapping
- spirometry
- slow vital capacity
- asthma
- Air trapping
- Asthma
- Epidemiology
- General population
- Obstructive
- Slow vital capacity
- Spirometry
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Toren, Kjell
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Olin, Anna-Carin
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Lindberg, Anne
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Vikgren, Jenny
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Schioler, Linus
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Brandberg, John
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visa fler...
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Johnsson, Ase
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Engström, Gunnar
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Persson, Lennart
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Skold, Magnus
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Hedner, Jan
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Lindberg, Eva
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Malinovschi, And ...
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Piitulainen, Eev ...
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Wollmer, Per
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Rosengren, Annik ...
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Janson, Christer
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Blomberg, Anders
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Bergstrom, Goran
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- MEDICIN OCH HÄLSOVETENSKAP
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och Klinisk medicin
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och Lungmedicin och ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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Uppsala universitet
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Linköpings universitet
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Lunds universitet
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Karolinska Institutet
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Umeå universitet