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  • Chen, LingjingKarolinska Institutet (författare)

Work Loss Duration and Predictors Following Rectal Cancer Treatment among Patients with and without Prediagnostic Work Loss

  • Artikel/kapitelEngelska2016

Förlag, utgivningsår, omfång ...

  • 2016
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-299052
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-299052URI
  • https://doi.org/10.1158/1055-9965.EPI-16-0112DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:133703597URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background: The number of working-age rectal cancer survivors is increasing due to early detection and improved treatment. However, work loss duration and predictors among them have not been studied thoroughly. Methods: We identified 3,438 patients with stage I-III rectal cancer, 18 to 61 years of age in the Swedish Colorectal Cancer Register 1996-2009. Information on work loss due to sick leave or disability pension was collected from 2 years before diagnosis to 5 years after (until December 31st, 2013). Incidence rate ratios (IRR) of work loss were estimated in a negative binominal model by clinical characteristics for the 1st and 2nd-5th years after diagnosis. Patients were stratified by prediagnostic work loss. Results: Patients without prediagnostic work loss (74%) experienced median 147 days (25th and 75th percentile: 55 and 281) of work loss during the 1st year after diagnosis. Work loss rates (2nd-5th years) were significantly increased among relapse-free patients diagnosed in stage III [IRR = 1.92; 95% confidence interval (CI), 1.52-2.43], operated with abdominoperineal resection (IRR = 1.26; 95% CI, 1.03-1.56), and treated with neoadjuvant (chemo) radiotherapy (IRR = 1.46; 95% CI, 1.06-2.02). Patients with prediagnostic work loss (26%) experienced median 336 days (25th and 75th percentile: 183 and 365) of work loss during the 1st year, and rates did not vary clinically till 5 years. Conclusion: Without prediagnostic work loss, disease-and treatment-related factors could help identify rectal cancer patients in need of early interventions to facilitate return to work. Impact: Clinical awareness around prediagnostic and postdiagnostic work loss and individualized cancer rehabilitation programs should be emphasized among cancer survivors.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Glimelius, IngridKarolinska Institutet,Uppsala universitet,Experimentell och klinisk onkologi,Karolinska Inst, Dept Med Solna, Clin Epidemiol Unit, Stockholm, Sweden.(Swepub:uu)inggl846 (författare)
  • Neovius, MartinKarolinska Institutet (författare)
  • Ekberg, SaraKarolinska Institutet (författare)
  • Martling, AnnaKarolinska Institutet (författare)
  • Eloranta, SandraKarolinska Institutet (författare)
  • Smedby, Karin E.Karolinska Institutet (författare)
  • Karolinska InstitutetExperimentell och klinisk onkologi (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Cancer Epidemiology, Biomarkers and Prevention25:6, s. 987-9941055-99651538-7755

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