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Tumor-induced neutr...
Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction
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- Cedervall, Jessica (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Dimberg, Anna (author)
- Uppsala universitet,Vaskulärbiologi
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- Olsson, Anna-Karin (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: Oncoimmunology. - 2162-4011 .- 2162-402X. ; 5:3
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Neutrophil extracellular traps (NETs) are part of the innate immune defense against microbes, but their contribution to several non-infectious inflammatory conditions has recently been unraveled. We demonstrate that NETs accumulate in the peripheral circulation in tumor-bearing mice, causing systemic inflammation and vascular dysfuntion in organs not affected by tumor cells.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- Cancer
- inflammation
- NETs
- neutrophil extracellular traps
- systemic
- vascular function
Publication and Content Type
- vet (subject category)
- art (subject category)
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