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Multidetector CT of...
Multidetector CT of pancreatic ductal adenocarcinoma : Effect of tube voltage and iodine load on tumour conspicuity and image quality
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- Loizou, L. (författare)
- Karolinska Institutet
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- Albiin, N. (författare)
- Karolinska Institutet
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- Leidner, B. (författare)
- Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden
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- Axelsson, E. (författare)
- Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden
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- Fischer, M. A. (författare)
- Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden
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- Grigoriadis, A. (författare)
- Karolinska Institutet
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- Del Chiaro, M. (författare)
- Karolinska Institutet
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- Segersvärd, R. (författare)
- Karolinska Institutet
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- Verbeke, C. (författare)
- Karolinska Institutet
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- Sundin, Anders (författare)
- Uppsala universitet,Radiologi,Univ Uppsala Hosp, Dept Radiol, S-75185 Uppsala, Sweden
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- Kartalis, N. (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2016-03-10
- 2016
- Engelska.
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Ingår i: European Radiology. - : Springer Science and Business Media LLC. - 0938-7994 .- 1432-1084. ; 26:11, s. 4021-4029
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: To compare a low-tube-voltage with or without high-iodine-load multidetector CT (MDCT) protocol with a normal-tube-voltage, normal-iodine-load (standard) protocol in patients with pancreatic ductal adenocarcinoma (PDAC) with respect to tumour conspicuity and image quality.METHODS: Thirty consecutive patients (mean age: 66 years, men/women: 14/16) preoperatively underwent triple-phase 64-channel MDCT examinations twice according to: (i) 120-kV standard protocol (PS; 0.75 g iodine (I)/kg body weight, n = 30) and (ii) 80-kV protocol A (PA; 0.75 g I/kg, n = 14) or protocol B (PB; 1 g I/kg, n = 16). Two independent readers evaluated tumour delineation and image quality blindly for all protocols. A third reader estimated the pancreas-to-tumour contrast-to-noise ratio (CNR). Statistical analysis was performed with the Chi-square test.RESULTS: Tumour delineation was significantly better in PB and PA compared with PS (P = 0.02). The evaluation of image quality was similar for the three protocols (all, P > 0.05). The highest CNR was observed with PB and was significantly better compared to PA (P = 0.02) and PS (P = 0.0002).CONCLUSION: In patients with PDAC, a low-tube-voltage, high-iodine-load protocol improves tumour delineation and CNR leading to higher tumour conspicuity compared to standard protocol MDCT.KEY POINTS: • Low-tube-voltage high-iodine-load MDCT improves pancreatic cancer conspicuity compared to a standard protocol. • The pancreas-to-tumour attenuation difference increases significantly by reducing the tube voltage. • The radiation exposure dose decreases by reducing the tube voltage.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- Pancreatic neoplasm; Image enhancement; Contrast media; Multidetector computed tomography; Radiation dosage
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Loizou, L.
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Albiin, N.
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Leidner, B.
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Axelsson, E.
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Fischer, M. A.
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Grigoriadis, A.
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Del Chiaro, M.
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Segersvärd, R.
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Verbeke, C.
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Sundin, Anders
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Kartalis, N.
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European Radiolo ...
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Uppsala universitet
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Karolinska Institutet