Sökning: onr:"swepub:oai:DiVA.org:uu-321337" >
Use of Swedish smok...
Use of Swedish smokeless tobacco (snus) and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA)
-
- Rasouli, B. (författare)
- Karolinska Institutet
-
- Andersson, T. (författare)
- Karolinska Institutet
-
- Carlsson, P-O (författare)
- Uppsala universitet,Transplantation och regenerativ medicin
-
visa fler...
-
- Grill, V. (författare)
- Norwegian Univ Sci & Technol, NTNU Inst Canc Res & Mol Med, Trondheim, Norway.;Univ Trondheim Hosp, Dept Endocrinol, Trondheim, Norway.
-
- Groop, L. (författare)
- Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden.
-
- Martinell, Mats, 1971- (författare)
- Uppsala universitet,Allmänmedicin och preventivmedicin
-
- Midthjell, K. (författare)
- Norwegian Univ Sci & Technol, Dept Community Med & Gen Practice, HUNT Res Ctr, Levanger, Norway.
-
- Storm, P. (författare)
- Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden.
-
- Tuomi, T. (författare)
- Univ Helsinki, Cent Hosp, Dept Med, Helsinki, Finland.;Univ Helsinki, Res Program Diabet & Obes, Helsinki, Finland.
-
- Carlsson, S. (författare)
- Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
- 2016-07-31
- 2017
- Engelska.
-
Ingår i: Diabetic Medicine. - : Wiley. - 0742-3071 .- 1464-5491. ; 34:4, s. 514-521
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- AimsIt has been suggested that moist snuff (snus), a smokeless tobacco product that is high in nicotine and widespread in Scandinavia, increases the risk of Type 2 diabetes. Previous studies are however few, contradictory and, with regard to autoimmune diabetes, lacking. Our aim was to study the association between snus use and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA). MethodAnalyses were based on incident cases (Type 2 diabetes, n = 724; LADA, n = 200) and population-based controls (n = 699) from a Swedish case-control study. Additional analyses were performed on cross-sectional data from the Norwegian HUNT study (n = 21 473) with 829 prevalent cases of Type 2 diabetes. Odds ratios (OR) were estimated adjusted for age, BMI family history of diabetes and smoking. Only men were included. ResultsNo association between snus use and Type 2 diabetes or LADA was seen in the Swedish data. For Type 2 diabetes, the OR for > 10 box-years was 1.00 [95% confidence interval (CI), 0.47 to 2.11] and for LADA 1.01 (95% CI, 0.45 to 2.29). Similarly, in HUNT, the OR for Type 2 diabetes in ever-users was estimated at 0.91 (95% CI, 0.75 to 1.10) and in heavy users at 0.92 (95% CI, 0.46 to 1.83). ConclusionThe risk of Type 2 diabetes and LADA is unrelated to the use of snus, despite its high nicotine content. This opens the possibility of the increased risk of Type 2 diabetes seen in smokers may not be attributed to nicotine, but to other substances in tobacco smoke.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Rasouli, B.
-
Andersson, T.
-
Carlsson, P-O
-
Grill, V.
-
Groop, L.
-
Martinell, Mats, ...
-
visa fler...
-
Midthjell, K.
-
Storm, P.
-
Tuomi, T.
-
Carlsson, S.
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Endokrinologi oc ...
- Artiklar i publikationen
-
Diabetic Medicin ...
- Av lärosätet
-
Uppsala universitet
-
Karolinska Institutet