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Sökning: onr:"swepub:oai:DiVA.org:uu-330023" > Multisite Assessmen...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00011712naa a2201117 4500
001oai:DiVA.org:uu-330023
003SwePub
008171009s2017 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3300232 URI
024a https://doi.org/10.1093/jnen/nlx0412 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Kovacs, Gabor G.u Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria.;Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
2451 0a Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG)
264 c 2017-06-07
264 1b Oxford University Press (OUP),c 2017
338 a print2 rdacarrier
520 a Aging-related tau astrogliopathy (ARTAG) is a recently introduced terminology. To facilitate the consistent identification of ARTAG and to distinguish it from astroglial tau pathologies observed in the primary frontotemporal lobar degeneration tauopathies we evaluated how consistently neuropathologists recognize (1) different astroglial tau immunoreactivities, including those of ARTAG and those associated with primary tauopathies (Study 1); (2) ARTAG types (Study 2A); and (3) ARTAG severity (Study 2B). Microphotographs and scanned sections immunostained for phosphorylated tau (AT8) were made available for download and preview. Percentage of agreement and kappa values with 95% confidence interval (CI) were calculated for each evaluation. The overall agreement for Study 1 was > 60% with a kappa value of 0.55 (95% CI 0.433-0.645). Moderate agreement (> 90%, kappa 0.48, 95% CI 0.457-0.900) was reached in Study 2A for the identification of ARTAG pathology for each ARTAG subtype (kappa 0.37-0.72), whereas fair agreement (kappa 0.40, 95% CI 0.341-0.445) was reached for the evaluation of ARTAG severity. The overall assessment of ARTAG showed moderate agreement (kappa 0.60, 95% CI 0.534-0.653) among raters. Our study supports the application of the current harmonized evaluation strategy for ARTAG with a slight modification of the evaluation of its severity.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a Aging
653 a ARTAG
653 a Digital pathology
653 a Interrater agreement
653 a Neuropathology
653 a Tau
653 a Tau-astrogliopathy
700a Xie, Sharon X.u Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.4 aut
700a Lee, Edward B.u Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
700a Robinson, John L.u Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
700a Caswell, Carrieu Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.4 aut
700a Irwin, David J.u Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
700a Toledo, Jon B.u Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
700a Johnson, Victoria E.u Univ Penn, Dept Neurosurg, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.4 aut
700a Smith, Douglas H.u Univ Penn, Dept Neurosurg, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.4 aut
700a Alafuzoff, Irinau Uppsala universitet,Klinisk och experimentell patologi4 aut0 (Swepub:uu)irial548
700a Attems, Johannesu Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England.4 aut
700a Bencze, Janosu Univ Debrecen, Dept Neuropathol, Inst Pathol, Fac Med, Debrecen, Hungary.4 aut
700a Bieniek, Kevin F.u Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.4 aut
700a Bigio, Eileen H.u Northwestern Univ, Feinberg Sch Med, Northwestern ADC Neuropathol Core, Chicago, IL 60611 USA.4 aut
700a Bodi, Istvanu Kings Coll Hosp London, Clin Neuropathol, London, England.;London Neurodegenerat Brain Bank, London, England.4 aut
700a Budka, Herbertu Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria.;Univ Hosp Zurich, Inst Neuropathol, Zurich, Switzerland.4 aut
700a Dickson, Dennis W.u Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.4 aut
700a Dugger, Brittany N.u Univ Calif San Francisco, Inst Neurodegenerat Dis, San Francisco, CA 94143 USA.4 aut
700a Duyckaerts, Charlesu UPMC Sorbonne Univ, Dept Neuropathol, Hop La Salpetriere, AP HP, Paris, France.4 aut
700a Ferrer, Isidrou Univ Barcelona, Inst Neuropathol, Bellvitge Univ Hosp, CIBERNED, Barcelona, Spain.4 aut
700a Forrest, Shelley L.u Univ Sydney, Sydney Med Sch, Discipline Pathol, Sydney, NSW, Australia.4 aut
700a Gelpi, Ellenu Inst Invest Biomed Pi &, Neurol Tissue Bank, Biobank Hosp Clin IDIBAPS, Barcelona, Spain.4 aut
700a Gentleman, Stephen M.u Imperial Coll London, Dept Med, London, England.4 aut
700a Giaccone, Giorgiou IRCCS Fdn Carlo Besta Neurol Inst, Milan, Italy.4 aut
700a Grinberg, Lea T.u Univ Calif San Francisco, Dept Neurol, Memory & Aging Ctr, San Francisco, CA USA.;Univ Sao Paulo, Sch Med, LIM, Dept Pathol, Sao Paulo, Brazil.4 aut
700a Halliday, Glenda M.u Univ Sydney, Brain & Mind Ctr, Sydney Med Sch, Sydney, NSW, Australia.;UNSW Med & NeuRA, Sydney, NSW, Australia.4 aut
700a Hatanpaa, Kimmo J.u Univ Texas Southwestern Med Ctr Dallas, Dept Pathol, Dallas, TX USA.4 aut
700a Hof, Patrick R.u Icahn Sch Med Mt Sinai, Fishberg Dept Neurosci, Friedman Brain Inst, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Ronald M Loeb Ctr Alzheimers Dis, New York, NY 10029 USA.4 aut
700a Hofer, Monikau John Radcliffe Hosp, Dept Neuropathol, Oxford, England.4 aut
700a Hortobagyi, Tiboru Univ Debrecen, Dept Neuropathol, Inst Pathol, Fac Med, Debrecen, Hungary.4 aut
700a Ironside, James W.u Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland.4 aut
700a King, Andrewu Kings Coll Hosp London, Clin Neuropathol, London, England.;London Neurodegenerat Brain Bank, London, England.4 aut
700a Kofler, Juliau Univ Pittsburgh, Dept Pathol, Pittsburgh, PA USA.4 aut
700a Kovari, Enikou Univ Hosp, Dept Mental Hlth & Psychiat, Geneva, Switzerland.;Univ Geneva, Sch Med, Geneva, Switzerland.4 aut
700a Kril, Jillian J.u Univ Sydney, Sydney Med Sch, Discipline Pathol, Sydney, NSW, Australia.4 aut
700a Love, Sethu Univ Bristol, Inst Clin Neurosci, Southmead Hosp, Learning & Res Level 2, Bristol, Avon, England.4 aut
700a Mackenzie, Ian R.u Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada.4 aut
700a Mao, Qinwenu Northwestern Univ, Feinberg Sch Med, Northwestern ADC Neuropathol Core, Chicago, IL 60611 USA.4 aut
700a Matej, Radoslavu Thomayer Hosp, Dept Pathol & Mol Med, Prague, Czech Republic.;Charles Univ Prague, Dept Pathol, Med Fac 1, Prague, Czech Republic.4 aut
700a McLean, Catrionau Alfred Hosp, Dept Anat Pathol, Prahran, Vic, Australia.4 aut
700a Munoz, David G.u St Michaels Hosp, Div Pathol, Toronto, ON, Canada.4 aut
700a Murray, Melissa E.u Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.4 aut
700a Neltner, Jannau Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.4 aut
700a Nelson, Peter T.u Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.4 aut
700a Ritchie, Dianeu Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland.4 aut
700a Rodriguez, Roberta D.u Univ Sao Paulo, Sch Med, Physiopathol Aging Lab, Brazilian Aging Brain Study Grp LIM22, Sao Paulo, Brazil.;Univ Sao Paulo, Behav & Cognit Neurol Unit, Dept Neurol, Sao Paulo, Brazil.4 aut
700a Rohan, Zdeneku Thomayer Hosp, Dept Pathol & Mol Med, Prague, Czech Republic.;Charles Univ Prague, Dept Pathol, Med Fac 1, Prague, Czech Republic.4 aut
700a Rozemuller, Annemiekeu Netherlands Brainbank, Amsterdam, Netherlands.;Vrije Univ Amsterdam, Dept Pathol, Med Ctr, Amsterdam, Netherlands.4 aut
700a Sakai, Kenjiu Kanazawa Univ, Grad Sch Med Sci, Dept Neurol & Neurobiol Aging, Kanazawa, Ishikawa, Japan.4 aut
700a Schultz, Christianu Heidelberg Univ, Inst Neuroanat, Ctr Biomed & Med Technol Mannheim, Med Fac Mannheim, Heidelberg, Germany.4 aut
700a Seilhean, Danielleu UPMC Sorbonne Univ, Dept Neuropathol, Hop La Salpetriere, AP HP, Paris, France.4 aut
700a Smith, Vanessau Univ Kentucky, Dept Pathol, Lexington, KY USA.;Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA.4 aut
700a Tacik, Pawelu Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA.;Univ Bonn, Med Ctr, Dept Neurodegenerat Dis & Gerontopsychiat, Bonn, Germany.4 aut
700a Takahashi, Hitoshiu Niigata Univ, Brain Res Inst, Dept Pathol, Niigata, Japan.4 aut
700a Takao, Masakiu Saitama Med Univ, Int Med Ctr, Dept Neurol, Saitama, Japan.4 aut
700a Thal, Dietmar Rudolfu Katholieke Univ Leuven, Dept Neurosci, Leuven, Belgium.;Univ Ziekenhuizen Leuven, Dept Pathol, Leuven, Belgium.4 aut
700a Weis, Sergeu Johannes Kepler Univ Linz, Neuropathol Lab, Dept Pathol & Neuropathol, Kepler Univ Hosp,Med Sch, Linz, Austria.4 aut
700a Wharton, Stephen B.u Univ Sheffield, Sheffield Inst Translat Neurosci, Sheffield, S Yorkshire, England.4 aut
700a White, Charles L., IIIu Univ Texas Southwestern Med Ctr Dallas, Dept Pathol, Dallas, TX USA.4 aut
700a Woulfe, John M.u Univ Ottawa, Dept Pathol & Lab Med, Ctr Canc Therapeut, Ottawa Hosp,Res Inst, Ottawa, ON, Canada.4 aut
700a Yamada, Masahitou Kanazawa Univ, Grad Sch Med Sci, Dept Neurol & Neurobiol Aging, Kanazawa, Ishikawa, Japan.4 aut
700a Trojanowski, John Q.u Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.4 aut
710a Med Univ Vienna, Inst Neurol, AKH 4J,Wahringer Gurtel 18-20, A-1097 Vienna, Austria.;Univ Penn, Ctr Neurodegenerat Dis Res, Inst Aging, Perelman Sch Med, Philadelphia, PA 19104 USA.;Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA.b Univ Penn, Dept Biostat & Epidemiol, Ctr Brain Injury & Repair, Philadelphia, PA 19104 USA.4 org
773t Journal of Neuropathology and Experimental Neurologyd : Oxford University Press (OUP)g 76:7, s. 605-619q 76:7<605-619x 0022-3069x 1554-6578
856u https://academic.oup.com/jnen/article-pdf/76/7/605/18158110/nlx041.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330023
8564 8u https://doi.org/10.1093/jnen/nlx041

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