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Ocular symptoms and...
Ocular symptoms and tear film break up time (BUT) among junior high school students in Penang, Malaysia - Associations with fungal DNA in school dust
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- Norbäck, Dan (författare)
- Uppsala universitet,Arbets- och miljömedicin
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- Hashim, Jamal Hisham (författare)
- United Nations Univ, Int Inst Global Hlth, Kuala Lumpur 56000, Malaysia.;Natl Univ Malaysia, Dept Community Hlth, Kuala Lumpur 56000, Malaysia.
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- Hashim, Zailina (författare)
- Univ Putra Malaysia, Dept Environm & Occupat Hlth, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia.
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- Sooria, Vinoshini (författare)
- Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Community Hlth, Serdang 43400, Selangor, Malaysia.
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- Ismail, Syazwan Aizat (författare)
- Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Community Hlth, Serdang 43400, Selangor, Malaysia.;Minist Hlth Malaysia, Allied Hlth Sci Coll Sg Buloh, Environm Hlth, Sungai Buloh 47000, Selangor, Malaysia.
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- Wieslander, Gunilla (författare)
- Uppsala universitet,Arbets- och miljömedicin
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(creator_code:org_t)
- ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2017
- 2017
- Engelska.
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Ingår i: International journal of hygiene and environmental health. - : ELSEVIER GMBH, URBAN & FISCHER VERLAG. - 1438-4639 .- 1618-131X. ; 220:4, s. 697-703
- Relaterad länk:
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http://collections.u...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: There are few studies on ocular effects of indoor mould exposure in schools, especially in the tropicsObjective: To study associations between eye symptoms and tear film break up time (BUT) in students and demographic data and fungal DNA in schools.Methods: A school environment study was performed among randomly selected students in eight randomly selected secondary schools in Penang, Malaysia. Information on eye symptoms and demographic data was collected by a standardised questionnaire. BUT was measured by two methods, self-reported BUT (SBUT) and by the non-invasive Tearscope (NIBUT). Dust was collected by vacuuming in 32 classrooms and analysed for five fungal DNA sequences. Geometric mean (GM) for total fungal DNA was 7.31*10(4) target copies per gram dust and for Aspergillus/Penicillium DNA 3.34*10(4) target copies per gram dust. Linear mixed models and 3-level multiple logistic regression were applied adjusting for demo-graphic factors.Results: A total of 368 students (58%) participated and 17.4% reported weekly eye symptoms the last 3 months. The median SBUT and TBUT were 15 and 12 s, respectively. Students wearing glasses (OR 2.41, p=0.01) and with a history of atopy (OR= 2.67; p=0.008) had more eye symptoms. Girls had less eye symptoms than boys (OR= 0.34; p=0.006) Indoor carbon dioxide in the classrooms was low (range 380-720 ppm), temperature was 25-30 degrees C and relative air humidity 70-88%. Total fungal DNA in vacuumed dust was associated with shorter SBUT (4s shorter per 10(5) target copies per gram dust; p=0.04) and NIBUT (4s shorter per 105 target copies per gram dust; p < 0.001). Aspergillus/Penicillium DNA was associated with shorter NIBUT (5 s shorter per 105 target copies per gram dust; p=0.01).Conclusion: Fungal contamination in schools in a tropical country can be a risk factor for impaired tear film stability among students.
Nyckelord
- Tear film break up time (BUT)
- Eye symptoms
- Mould
- School environment
- Fungal DNA
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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