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Comparing very low ...
Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants
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- Koller-Smith, Louise I. M. (författare)
- Univ Technol Sydney, Fac Hlth Sci, Sydney, NSW, Australia.
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- Shahr, Prakesh S. (författare)
- Mt Sinai Hosp, Dept Pediat, Toronto, ON, Canada.;Univ Toronto, Toronto, ON, Canada.;Mt Sinai Hosp, Maternal Infant Care Res Ctr, Toronto, ON, Canada.
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- Ye, Xiang Y. (författare)
- Mt Sinai Hosp, Maternal Infant Care Res Ctr, Toronto, ON, Canada.
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- Sjörs, Gunnar (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning
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- Wang, Yueping A. (författare)
- Univ Technol Sydney, Fac Hlth Sci, Sydney, NSW, Australia.
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- Chow, Sharon S. W. (författare)
- Univ Technol Sydney, Fac Hlth Sci, Sydney, NSW, Australia.
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- Darlow, Brian A. (författare)
- Univ Otago, Dept Paediat, Christchurch, New Zealand.
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- Lee, Shoo K. (författare)
- Mt Sinai Hosp, Dept Pediat, Toronto, ON, Canada.;Univ Toronto, Toronto, ON, Canada.;Mt Sinai Hosp, Maternal Infant Care Res Ctr, Toronto, ON, Canada.
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- Håkansson, Stellan (författare)
- Umeå universitet,Pediatrik
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- Lui, Kei (författare)
- Univ Technol Sydney, Fac Hlth Sci, Sydney, NSW, Australia.;Royal Hosp Women, Dept Newborn Care, Barker St, Sydney, NSW 2031, Australia.
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Univ Technol Sydney, Fac Hlth Sci, Sydney, NSW, Australia Mt Sinai Hosp, Dept Pediat, Toronto, ON, Canada.;Univ Toronto, Toronto, ON, Canada.;Mt Sinai Hosp, Maternal Infant Care Res Ctr, Toronto, ON, Canada. (creator_code:org_t)
- 2017-07-14
- 2017
- Engelska.
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Ingår i: BMC Pediatrics. - : Springer Science and Business Media LLC. - 1471-2431. ; 17
- Relaterad länk:
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https://doi.org/10.1...
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https://bmcpediatr.b...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact upon the validity of data for benchmarking purposes. Method: Data from all VLGA or VLBW infants admitted in the 3 Networks between 2008 and 2011 were used. Two-thirds of each network cohort was randomly selected to develop prediction models for mortality and composite adverse outcome (CAO: mortality or cerebral injuries, chronic lung disease, severe retinopathy or necrotizing enterocolitis) and the remaining for internal validation. Areas under the ROC curves (AUC) of themodels were compared. Results: VLBW cohort (24,335 infants) had twice more SGA infants (20.4% vs. 9.3%) than the VLGA cohort (29,180 infants) and had a higher rate of CAO (36.5% vs. 32.6%). The two models had equal prediction power for mortality and CAO (AUC 0.83), and similarly for all other cross-cohort validations (AUC 0.81-0.85). Neither model performed well for the extremes of birth weight for gestation (<1500 g and >= 32 weeks, AUC 0.50-0.65; >= 1500 g and >= 32 weeks, AUC 0.60-0.62). Conclusion: There was no difference in prediction power for adverse outcome between cohorting VLGA or VLBW despite substantial bias in SGA population. Either cohorting practises are suitable for international benchmarking.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Outcome
- Intensive care
- Neonatal
- Infant
- Premature
- Very low birth weight
- Small for gestational age
- Benchmarking
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Koller-Smith, Lo ...
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Shahr, Prakesh S ...
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Ye, Xiang Y.
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Sjörs, Gunnar
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Wang, Yueping A.
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Chow, Sharon S. ...
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visa fler...
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Darlow, Brian A.
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Lee, Shoo K.
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Håkansson, Stell ...
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Lui, Kei
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Reproduktionsmed ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
- Artiklar i publikationen
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BMC Pediatrics
- Av lärosätet
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Uppsala universitet
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Umeå universitet