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Fully covered stent...
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Persson, Jan,1962Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
(författare)
Fully covered stents are similar to semi-covered stents with regard to migration in palliative treatment of malignant strictures of the esophagus and gastric cardia : results of a randomized controlled trial.
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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2017-02-24
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Springer Science and Business Media LLC,2017
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-333272
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-333272URI
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https://doi.org/10.1007/s00464-017-5441-0DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136849989URI
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https://gup.ub.gu.se/publication/254807URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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INTRODUCTION: Stent migration is a significant clinical problem in palliation of malignant strictures in the esophagus and gastro-esophageal junction (GEJ). We have compared a newer design of a fully-covered stent to a widely used semi-covered stent using migration >20 mm as the primary outcome variable. Effects on dysphagia, quality of life (QoL) and re-intervention frequency were also investigated.METHODS: Patients with dysphagia due to non-curable esophagus/GEJ cancer were randomized to receive either a more recent design of a fully-covered stent (n = 48) or a conventional semi-covered stent (n = 47). Chest x-ray, dysphagia and QoL were studied at baseline, one week, four weeks and three months thereafter.RESULTS: There were no significant differences either in stent migration distance or in the migration frequency. Stent migration during the total study period occurred in 37.2 % in the semi-covered group compared to 20.0 % for the fully-covered group. Dysphagia was measured with Watson and Ogilvie scores and with the dysphagia module in the QoL scale (QLQ-OG25). On average, there was a tendency to better dysphagia relief for the fully-covered design as scored with the two latter dysphagia instruments (p= 0.081 and p= 0.067) at three months and towards more re-interventions in the semi-covered group (p= 0.083).CONCLUSION: In spite of its somewhat lower intrinsic radial force, the fully-covered stent was comparable to the conventional semi-covered stent with regard to stent migration. The data further suggest a potential benefit of the fully-covered stent in improving dysphagia in patients with longer life expectancy.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Smedh, Ulrika,1966Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery(Swepub:gu)xsmeul
(författare)
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Johnsson, Åse (Allansdotter),1966Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology(Swepub:gu)xjohna
(författare)
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Ohlin, BoBlekinge Hosp, Dept Surg, Karlskrona, Sweden
(författare)
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Sundbom, MagnusUppsala universitet,Gastrointestinalkirurgi(Swepub:uu)magsundb
(författare)
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Nilsson, MagnusKarolinska Institutet
(författare)
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Lundell, LarsKarolinska Institutet
(författare)
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Sund, BeritKarolinska Inst, Karolinska Univ Hosp, Div Surg, Dept Surg Gastroenterol,CLINTEC, Stockholm, Sweden
(författare)
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Johnsson, Erik,1966Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery(Swepub:gu)xjoher
(författare)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för kirurgi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Surgical Endoscopy: Springer Science and Business Media LLC31:10, s. 4025-40330930-27941432-2218
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Persson, Jan, 19 ...
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Smedh, Ulrika, 1 ...
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Johnsson, Åse (A ...
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Ohlin, Bo
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Sundbom, Magnus
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Nilsson, Magnus
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visa fler...
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Lundell, Lars
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Sund, Berit
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Johnsson, Erik, ...
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