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Fruit and vegetable...
Fruit and vegetable consumption and risk of COPD : a prospective cohort study of men.
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Kaluza, Joanna (författare)
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- Larsson, Susanna C (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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- Orsini, Nicola (författare)
- Karolinska Institutet
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- Linden, Anders (författare)
- Karolinska Institutet
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- Wolk, Alicja (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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visa färre...
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(creator_code:org_t)
- 2017-02-22
- 2017
- Engelska.
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Ingår i: Thorax. - : BMJ. - 0040-6376 .- 1468-3296. ; 72:6, s. 500-509
- Relaterad länk:
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https://thorax.bmj.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Antioxidants present in fruits and vegetables may protect the lung from oxidative damage and prevent COPD.AIMS: To determine the association between fruit and vegetable consumption and risk of COPD by smoking status in men.METHODS: The population-based prospective Cohort of Swedish Men included 44 335 men, aged 45-79 years, with no history of COPD at baseline. Fruit and vegetable consumption was assessed with a self-administered questionnaire.RESULTS: During a mean follow-up of 13.2 years, 1918 incident cases of COPD were ascertained. A strong inverse association between total fruit and vegetable consumption and COPD was observed in smokers but not in never-smokers (p-interaction=0.02). The age-standardised incidence rate per 100 000 person-years in the lowest quintile (<2 servings/day) of total fruit and vegetable consumption was 1166 in current smokers and 506 in ex-smokers; among those in the highest quintile (≥5.3 servings/day), 546 and 255 per 100 000 person-years, respectively. The multivariable HR of COPD comparing extreme quintiles of total fruit and vegetable consumption was 0.60 (95% CI 0.47 to 0.76, p-trend <0.0001) in current smokers and 0.66 (95% CI 0.51 to 0.85, p-trend=0.001) in ex-smokers. Each one serving per day increment in total fruit and vegetable consumption decreased risk of COPD significantly by 8% (95% CI 4% to 11%) in current smokers and by 4% (95% CI 0% to 7%) in ex-smokers.CONCLUSIONS: These results indicate that high consumption of fruits and vegetables is associated with reduced COPD incidence in both current and ex-smokers but not in never-smokers.
Nyckelord
- COPD epidemiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Thorax
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