Sökning: onr:"swepub:oai:DiVA.org:uu-341015" >
Online HPLC-ESI-HRM...
Online HPLC-ESI-HRMS Method for the Analysis and Comparison of Different Dissolved Organic Matter Samples
-
- Patriarca, Claudia (författare)
- Uppsala universitet,Analytisk kemi
-
- Bergquist, Jonas (författare)
- Uppsala universitet,Analytisk kemi
-
- Sjöberg, Per JR (författare)
- Uppsala universitet,Analytisk kemi
-
visa fler...
-
- Tranvik, Lars (författare)
- Uppsala universitet,Limnologi
-
- Hawkes, Jeffrey A. (författare)
- Uppsala universitet,Analytisk kemi
-
visa färre...
-
(creator_code:org_t)
- 2018-01-04
- 2018
- Engelska.
-
Ingår i: Environmental Science and Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 52:4, s. 2091-2099
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Natural dissolved organic matter (DOM) is an ultracomplex mixture that is essential to global carbon cycling but is poorly understood because of its complexity. The most powerful tool for the DOM characterization is high-resolution mass spectrometry (HRMS) generally combined to direct infusion (DI) as sample introduction. Liquid chromatography (LC) represents a compelling alternative to DI; however, state-of-the-art techniques involve only offline LC-HRMS approaches, which have important logistical drawbacks that make DOM analysis more challenging. This study introduces a new method based on online coupling of liquid chromatography to high resolution mass spectrometry, able to overcome the disadvantages of usual approaches. It is characterized by high reproducibility (% Bray–Curtis dissimilarity among replicates ≈ 2.5%), and it reduces transient complexity and contaminant interferences, thus increasing the signal-to-noise ratio (S/N), leading to the identification of an overall larger number of formulas in the mixture. Moreover, the application of an in silico fractionation prior to the statistical analysis allows an easy, flexible, fast, and detailed comparison of DOM samples from a variety of sources with a single chromatographic run.
Ämnesord
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
Nyckelord
- Kemi med inriktning mot analytisk kemi
- Chemistry with specialization in Analytical Chemistry
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas