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Sökning: onr:"swepub:oai:DiVA.org:uu-341481" > Regional gastrointe...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005097naa a2200433 4500
001oai:DiVA.org:uu-341481
003SwePub
008180228s2018 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3414812 URI
0247 a https://doi.org/10.1111/apt.144382 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Farmer, A. D.u Aalborg Univ, Aalborg Univ Hosp, Aalborg & Clin Inst, Mech Sense,Dept Gastroenterol & Hepatol, Aalborg, Denmark.;Queen Mary Univ London, Neurogastroenterol Grp, Ctr Neurosci & Trauma, Blizard Inst,Wingate Inst Neurogastroenterol,Bart, London, England.;Univ Hosp North Midlands, Dept Gastroenterol, Stoke On Trent, Staffs, England.4 aut
2451 0a Regional gastrointestinal contractility parameters using the wireless motility capsule :b inter-observer reproducibility and influence of age, gender and study country
264 c 2017-12-06
264 1b Wiley,c 2018
338 a print2 rdacarrier
520 a Background:The wireless motility capsule concurrently measures temperature, pH and pressure as it traverses the gastrointestinal tract. Aims: To describe normative values for motility/contractility parameters across age, gender and testing centres.Methods:Healthy participants underwent a standardised wireless motility capsule assessment following an overnight fast and consumption of a meal of known nutritional content. Traces were divided into regions of interest and analysed using 2 software packages (MotiliGI and GIMS Data Viewer). Inter-observer agreement was independently assessed by 2 investigators.Results:Normative data for motility/contractility parameters (maximum amplitude, mean peak amplitude, contraction frequency and motility index) are presented for 107 individuals (62 male, median age 40years, range 18-78). MotiliGI-Gastric, small bowel and colonic maximal contraction amplitude correlated with age (r = .24, P = .01; r = .22, P = .02; and r = .2, P = .04 respectively). Small bowel motility index was higher in females than males (150.412 vs 122 +/- 7.6, P = .04). Inter-observer agreement was excellent for transit times, pH and contractility/motility parameters. GIMS Data viewer-Gastric, small bowel and colonic log(e) motility index correlated with the respective area under the contraction curve, total contractions, sum of amplitudes and contraction frequency (all r>.35, P < .0003) but not with transit times.Conclusions: Our analysis provides normative data for motility/contractility parameters. Log motility index summarises a number of measures. In future, the measurement of contractile activity with the wireless motility capsule may potentially aid in the diagnosis of disease states such as visceral myopathic disorders.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
7001 a Wegeberg, A. -ML.4 aut
7001 a Brock, B.u Aarhus Univ Hosp, Dept Clin Biochem, Aarhus, Denmark.4 aut
7001 a Hobson, A. R.u Funct Gut Clin, London, England.4 aut
7001 a Mohammed, S. D.u Queen Mary Univ London, Neurogastroenterol Grp, Ctr Neurosci & Trauma, Blizard Inst,Wingate Inst Neurogastroenterol,Bart, London, England.4 aut
7001 a Scott, S. M.u Queen Mary Univ London, Neurogastroenterol Grp, Ctr Neurosci & Trauma, Blizard Inst,Wingate Inst Neurogastroenterol,Bart, London, England.4 aut
7001 a Bruckner-Holt, C. E.u Univ Hosp North Midlands, Dept Gastroenterol, Stoke On Trent, Staffs, England.4 aut
7001 a Semler, J. R.u Medtronic, Sunnyvale, CA USA.4 aut
7001 a Hasler, W. L.u Univ Michigan Hlth Syst, Div Gastroenterol, Ann Arbor, MI USA.4 aut
7001 a Hellström, Per M.,d 1954-u Uppsala universitet,Gastroenterologi/hepatologi4 aut0 (Swepub:uu)perhe742
7001 a Drewes, A. M.u Aalborg Univ, Aalborg Univ Hosp, Aalborg & Clin Inst, Mech Sense,Dept Gastroenterol & Hepatol, Aalborg, Denmark.4 aut
7001 a Brock, C.u Aalborg Univ, Aalborg Univ Hosp, Aalborg & Clin Inst, Mech Sense,Dept Gastroenterol & Hepatol, Aalborg, Denmark.;Univ Copenhagen, Dept Pharmacotherapy & Dev, Copenhagen, Denmark.4 aut
7102 a Aalborg Univ, Aalborg Univ Hosp, Aalborg & Clin Inst, Mech Sense,Dept Gastroenterol & Hepatol, Aalborg, Denmark.;Queen Mary Univ London, Neurogastroenterol Grp, Ctr Neurosci & Trauma, Blizard Inst,Wingate Inst Neurogastroenterol,Bart, London, England.;Univ Hosp North Midlands, Dept Gastroenterol, Stoke On Trent, Staffs, England.b Aarhus Univ Hosp, Dept Clin Biochem, Aarhus, Denmark.4 org
7730 t Alimentary Pharmacology and Therapeuticsd : Wileyg 47:3, s. 391-400q 47:3<391-400x 0269-2813x 1365-2036
8564 u http://qmro.qmul.ac.uk/xmlui/handle/123456789/31274
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-341481
8564 8u https://doi.org/10.1111/apt.14438

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