Sökning: onr:"swepub:oai:DiVA.org:uu-350613" > A comprehensive gen...
Fältnamn | Indikatorer | Metadata |
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000 | 08504naa a2200865 4500 | |
001 | oai:DiVA.org:uu-350613 | |
003 | SwePub | |
008 | 180523s2018 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:nrm-3133 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3506132 URI |
024 | 7 | a https://doi.org/10.1073/pnas.17205541152 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-31332 URI |
040 | a (SwePub)uud (SwePub)nrm | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Palkopoulou, Eleftheriau Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
245 | 1 0 | a A comprehensive genomic history of extinct and living elephants |
264 | c 2018-02-26 | |
264 | 1 | b NATL ACAD SCIENCES,c 2018 |
338 | a print2 rdacarrier | |
520 | a Elephantids are the world's most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a total of 14 genomes, including 2 from the American mastodon, which is an extinct elephantid relative, and 12 spanning all three extant and three extinct elephantid species including an similar to 120,000-y-old straight-tusked elephant, a Columbian mammoth, and woolly mammoths. Earlier genetic studies modeled elephantid evolution via simple bifurcating trees, but here we show that interspecies hybridization has been a recurrent feature of elephantid evolution. We found that the genetic makeup of the straight-tusked elephant, previously placed as a sister group to African forest elephants based on lower coverage data, in fact comprises three major components. Most of the straight-tusked elephant's ancestry derives from a lineage related to the ancestor of African elephants while its remaining ancestry consists of a large contribution from a lineage related to forest elephants and another related to mammoths. Columbian and woolly mammoths also showed evidence of interbreeding, likely following a latitudinal cline across North America. While hybridization events have shaped elephantid history in profound ways, isolation also appears to have played an important role. Our data reveal nearly complete isolation between the ancestors of the African forest and savanna elephants for similar to 500,000 y, providing compelling justification for the conservation of forest and savanna elephants as separate species. | |
650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
653 | a paleogenomics | |
653 | a elephantid evolution | |
653 | a mammoth | |
653 | a admixture | |
653 | a species divergence | |
653 | a Diversity of life | |
700 | 1 | a Lipson, Marku Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 aut |
700 | 1 | a Mallick, Swapanu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
700 | 1 | a Nielsen, Svendu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut |
700 | 1 | a Rohland, Nadinu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 aut |
700 | 1 | a Baleka, Sinau Univ Potsdam, Unit Gen Zool Evolutionary Adapt Genom, Inst Biochem & Biol, Fac Math & Life Sci, D-14476 Potsdam, Germany.4 aut |
700 | 1 | a Karpinski, Emilu McMaster Univ, McMaster Ancient DNA Ctr, Dept Anthropol, Hamilton, ON L8S 4L9, Canada.;McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada.;McMaster Univ, Dept Biochem, Hamilton, ON L8S 4L8, Canada.;McMaster Univ, Michael G DeGroote Inst Infect Dis Res, Hamilton, ON L8S 4L8, Canada.4 aut |
700 | 1 | a Ivancevici, Atma M.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a To, Thu-Hien4 aut |
700 | 1 | a Kortschak, Danielu Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a Raison, Joy M.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a Qu, Zhipengu Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a Chin, Tat-Junu Univ Adelaide, Sch Comp Sci, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a Alt, Kurt W.u Danube Private Univ, Ctr Nat & Cultural Human Hist, A-3500 Krems, Austria.;Univ Basel, Univ Basel Hosp, Dept Biomed Engn, CH-4123 Basel, Switzerland.;Univ Basel, Integrat Prehist & Archaeol Sci, CH-4051 Basel, Switzerland.4 aut |
700 | 1 | a Claesson, Stefanu Inst Maritime Hist, Tall Timbers, MD 20690 USA.4 aut |
700 | 1 | a Dalén, Loveu Naturhistoriska riksmuseet,Enheten för bioinformatik och genetik4 aut0 (Swepub:nrm)lovedale |
700 | 1 | a MacPhee, Ross D. E.u Amer Museum Nat Hist, Div Vertebrate Zool Mammal, New York, NY 10024 USA.4 aut |
700 | 1 | a Meller, Haraldu State Off Heritage Management & Archaeol, D-06114 Halle, Saale, Germany.4 aut |
700 | 1 | a Rocar, Alfred L.u Univ Illinois, Dept Anim Sci, Urbana, IL 61801 USA.;Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA.4 aut |
700 | 1 | a Ryder, Oliver A.u San Diego Zoo, Inst Conservat Res, Escondido, CA 92027 USA.4 aut |
700 | 1 | a Heiman, Davidu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
700 | 1 | a Young, Sarahu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
700 | 1 | a Breen, Matthewu North Carolina State Univ, Coll Vet Med, Dept Mol Biomed Sci, Raleigh, NC 27607 USA.4 aut |
700 | 1 | a Williams, Christinau North Carolina State Univ, Coll Vet Med, Dept Mol Biomed Sci, Raleigh, NC 27607 USA.4 aut |
700 | 1 | a Aken, Bronwen L.u European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England.;Wellcome Sanger Inst, Cambridge CB10 1SD, England.4 aut |
700 | 1 | a Ruffier, Magaliu European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England.;Wellcome Sanger Inst, Cambridge CB10 1SD, England.4 aut |
700 | 1 | a Karlsson, Elinoru Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Univ Massachusetts, Sch Med, Program Bioinformat & Integrat Biol, Worcester, MA 01655 USA.4 aut |
700 | 1 | a Johnson, Jeremyu Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
700 | 1 | a Di Palma, Federicau Earlham Inst, Norwich NR4 7UZ, Norfolk, England.4 aut |
700 | 1 | a Alfoldi, Jessicau Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.4 aut |
700 | 1 | a Adelsoni, David L.u Univ Adelaide, Sch Biol Sci, Dept Genet & Evolut, Adelaide, SA 5005, Australia.4 aut |
700 | 1 | a Mailund, Thomasu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut |
700 | 1 | a Munch, Kasperu Aarhus Univ, Bioinformat Res Ctr, DK-8000 Aarhus, Denmark.4 aut |
700 | 1 | a Lindblad-Toh, Kerstinu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab,Broad Inst MIT & Harvard, Cambridge, MA 02142 USA4 aut0 (Swepub:uu)kerli865 |
700 | 1 | a Hofreiter, Michaelu Univ Potsdam, Unit Gen Zool Evolutionary Adapt Genom, Inst Biochem & Biol, Fac Math & Life Sci, D-14476 Potsdam, Germany.4 aut |
700 | 1 | a Poinar, Hendriku McMaster Univ, McMaster Ancient DNA Ctr, Dept Anthropol, Hamilton, ON L8S 4L9, Canada.;McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada.;McMaster Univ, Dept Biochem, Hamilton, ON L8S 4L8, Canada.;McMaster Univ, Michael G DeGroote Inst Infect Dis Res, Hamilton, ON L8S 4L8, Canada.4 aut |
700 | 1 | a Reich, Davidu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Howard Hughes Med Inst, Boston, MA 02115 USA.4 aut |
710 | 2 | a Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.b Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.4 org |
773 | 0 | t Proceedings of the National Academy of Sciences of the United States of Americad : NATL ACAD SCIENCESg 115:11, s. E2566-E2574q 115:11<E2566-E2574x 0027-8424x 1091-6490 |
856 | 4 | u https://www.pnas.org/content/pnas/115/11/E2566.full.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-350613 |
856 | 4 8 | u https://doi.org/10.1073/pnas.1720554115 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-3133 |
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