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Health care resourc...
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Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning
(författare)
Health care resource utilization and cost for asthma patients regularly treated with oral corticosteroids - a Swedish observational cohort study (PACEHR)
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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2018-09-03
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BMC,2018
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electronicrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-364248
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-364248URI
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https://doi.org/10.1186/s12931-018-0855-3DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:139086112URI
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Språk:engelska
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Sammanfattning på:engelska
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Background: Patients with severe uncontrolled asthma may receive oral corticosteroid (OCS) treatment regularly. The present study investigated the health care resource utilization and cost in regularly OCS treated Swedish asthma patients.Methods: Primary care medical records data were linked to data from Swedish national health registries. Patients >= 18 years with a drug claim for obstructive pulmonary diseases during 2007-2009 (index date) and a prior asthma diagnosis, were classified by their OCS claims during the 12-months' post index period: regular OCS equals >= 5 mg per day; periodic OCS less than 5 mg per day; or non-OCS users. Cost of asthma-and OCS-morbidity-related health care resource utilization were calculated.Results: A total of 15,437 asthma patients (mean age 47.8, female 62.6%), whereof 223 (1.44%) were regular OCS users, 3054 (19.7%) were periodic, and 12,160 (78.7%) were non-OCS users. Regular OCS users were older and more often females, had lower lung function, greater eosinophil count and more co-morbidities at baseline compared with the other groups. Age-adjusted annual total health care cost was three-times greater in the regular OCS group ((sic)5615) compared with the non-OCS users ((SIC) 1980) and twice as high as in the periodic OCS group ((sic) 2948). The major cost driver in the non-OCS and periodic OCS groups were primary care consultations, whereas inpatient costs were the major cost driver in the regular OCS group. The asthma related costs represented 10-12% of the total cost in all three groups.Conclusion: In this real-life asthma study in Sweden, the total yearly cost of health care resource utilization for a regular OCS user was three times greater than for a patient with no OCS use, indicating substantial economic and health care burden for asthma patients on regular oral steroid treatment.
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Johansson, GunnarUppsala universitet,Allmänmedicin och preventivmedicin(Swepub:uu)gunnarjs
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Telg, GunillaAstraZeneca Nord Baltic, Sodertalje, Sweden
(författare)
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Thuresson, MarcusStatisticon AB, Uppsala, Sweden
(författare)
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Christensen, Helene NordahlAstraZeneca Nord Baltic, Sodertalje, Sweden
(författare)
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Larsson, KjellKarolinska Institutet,Karolinska Inst, Natl Inst Environm Med, Solna, Sweden
(författare)
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Uppsala universitetLung- allergi- och sömnforskning
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Respiratory Research: BMC191465-99211465-993X
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