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High birth weight w...
High birth weight was associated with increased radial artery intima thickness but not with other investigated cardiovascular risk factors in adulthood
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- Johnsson, Inger W, 1973- (författare)
- Uppsala universitet,Pediatrisk inflammationsforskning
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- Naessén, Tord (författare)
- Uppsala universitet,Gynekologisk endokrinologi
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- Ahlsson, Fredrik, 1967- (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning
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- Gustafsson, Jan, 1948- (författare)
- Uppsala universitet,Pediatrisk inflammationsforskning
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(creator_code:org_t)
- 2018-06-14
- 2018
- Engelska.
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 12, s. 2152-2157
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- AIM: This study investigated whether a high birth weight was associated with increased risk factors for cardiovascular disease when Swedish adults reached 34-40.METHODS: We studied 27 subjects born at Uppsala University Hospital in 1975-1979, weighing at least 4500 g, and compared them with 27 controls selected by the Swedish National Board of Welfare with birth weights within ±1 standard deviations scores and similar ages and gender. The study included body mass index (BMI), blood pressure, lipid profile, haemoglobin A1c (HbA1c), C-reactive protein (CRP) and high-frequency ultrasound measurements of intima-media thickness, intima thickness (IT) and intima:media ratio of the carotid and radial arteries.RESULTS: Subjects with a high birth weight did not differ from controls with regard to BMI, blood pressure, lipid profile, high-sensitivity CRP, HbA1c or carotid artery wall dimensions. However, their radial artery intima thickness was 37% greater than the control group and their intima:media ratio was 44% higher.CONCLUSION: Our findings indicate that a high birth weight was associated with increased radial artery intima thickness, but not with other investigated cardiovascular risk factors, at 34-40 years of age. The clinical implications of these findings should be investigated further, especially in subjects born with a very high birth weight.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Cardiovascular risk factors
- High birth weight
- Intima thickness
- Intima:media ratio
- Large for gestational age
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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