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Thiazolidine chemis...
Thiazolidine chemistry revisited : a fast, efficient and stable click-type reaction at physiological pH
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- Bermejo-Velasco, Daniel (författare)
- Uppsala universitet,Polymerkemi
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- Nawale, Ganesh N. (författare)
- Uppsala universitet,Polymerkemi
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- Oommen, Oommen P. (författare)
- Bioengineering and Nanomedicine Lab, Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, and BioMediTech Institute, 33720, Tampere, Finland
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- Hilborn, Jöns, 1956- (författare)
- Uppsala universitet,Polymerkemi
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- Varghese, Oommen P., 1977- (författare)
- Uppsala universitet,Polymerkemi
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(creator_code:org_t)
- 2018
- 2018
- Engelska.
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 54:88, s. 12507-12510
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://pubs.rsc.org...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- We describe the fast reaction kinetics between 1,2-aminothiols and aldehydes. Under physiological conditions such a click-type reaction afforded a thiazolidine product that remains stable and did not require any catalyst. This type of bioorthogonal reaction offers enormous potential for the coupling of biomolecules in an efficient and biocompatible manner.
Ämnesord
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
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