Sökning: onr:"swepub:oai:DiVA.org:uu-365778" >
The LAS VEGAS risk ...
The LAS VEGAS risk score for prediction of postoperative pulmonary complications : An observational study
-
Neto, Ary Serpa (författare)
-
da Costa, Luiz Guilherme V (författare)
-
Hemmes, Sabrine N T (författare)
-
visa fler...
-
Canet, Jaume (författare)
-
- Hedenstierna, Göran, 1941- (författare)
- Uppsala universitet,Klinisk fysiologi,Hedenstiernalaboratoriet
-
Jaber, Samir (författare)
-
Hiesmayr, Michael (författare)
-
Hollmann, Markus W (författare)
-
Mills, Gary H (författare)
-
Vidal Melo, Marcos F (författare)
-
Pearse, Rupert (författare)
-
Putensen, Christian (författare)
-
Schmid, Werner (författare)
-
Severgnini, Paolo (författare)
-
Wrigge, Hermann (författare)
-
Gama de Abreu, Marcelo (författare)
-
Pelosi, Paolo (författare)
-
Schultz, Marcus J (författare)
-
visa färre...
-
(creator_code:org_t)
- 2018
- 2018
- Engelska.
-
Ingår i: European Journal of Anaesthesiology. - 0265-0215 .- 1365-2346. ; 35:9, s. 691-701
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- BACKGROUND: Currently used pre-operative prediction scores for postoperative pulmonary complications (PPCs) use patient data and expected surgery characteristics exclusively. However, intra-operative events are also associated with the development of PPCs.OBJECTIVE: We aimed to develop a new prediction score for PPCs that uses both pre-operative and intra-operative data.DESIGN: This is a secondary analysis of the LAS VEGAS study, a large international, multicentre, prospective study.SETTINGS: A total of 146 hospitals across 29 countries.PATIENTS: Adult patients requiring intra-operative ventilation during general anaesthesia for surgery.INTERVENTIONS: The cohort was randomly divided into a development subsample to construct a predictive model, and a subsample for validation.MAIN OUTCOME MEASURES: Prediction performance of developed models for PPCs.RESULTS: Of the 6063 patients analysed, 10.9% developed at least one PPC. Regression modelling identified 13 independent risk factors for PPCs: six patient characteristics [higher age, higher American Society of Anesthesiology (ASA) physical score, pre-operative anaemia, pre-operative lower SpO2 and a history of active cancer or obstructive sleep apnoea], two procedure-related features (urgent or emergency surgery and surgery lasting ≥ 1 h), and five intra-operative events [use of an airway other than a supraglottic device, the use of intravenous anaesthetic agents along with volatile agents (balanced anaesthesia), intra-operative desaturation, higher levels of positive end-expiratory pressures > 3 cmH2O and use of vasopressors]. The area under the receiver operating characteristic curve of the LAS VEGAS risk score for prediction of PPCs was 0.78 [95% confidence interval (95% CI), 0.76 to 0.80] for the development subsample and 0.72 (95% CI, 0.69 to 0.76) for the validation subsample.CONCLUSION: The LAS VEGAS risk score including 13 peri-operative characteristics has a moderate discriminative ability for prediction of PPCs. External validation is needed before use in clinical practice.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, number NCT01601223.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- Anestesiologi och intensivvård
- Anaesthesiology and Intensive Care
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Neto, Ary Serpa
-
da Costa, Luiz G ...
-
Hemmes, Sabrine ...
-
Canet, Jaume
-
Hedenstierna, Gö ...
-
Jaber, Samir
-
visa fler...
-
Hiesmayr, Michae ...
-
Hollmann, Markus ...
-
Mills, Gary H
-
Vidal Melo, Marc ...
-
Pearse, Rupert
-
Putensen, Christ ...
-
Schmid, Werner
-
Severgnini, Paol ...
-
Wrigge, Hermann
-
Gama de Abreu, M ...
-
Pelosi, Paolo
-
Schultz, Marcus ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Anestesi och int ...
- Artiklar i publikationen
-
European Journal ...
- Av lärosätet
-
Uppsala universitet