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Fish, long-chain om...
Fish, long-chain omega-3 polyunsaturated fatty acid intake and incidence of atrial fibrillation : A pooled analysis of two prospective studies
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- Larsson, Susanna C (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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- Wolk, Alicja (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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(creator_code:org_t)
- Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Clinical Nutrition. - : Elsevier. - 0261-5614 .- 1532-1983. ; 36:2, s. 537-541
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND & AIMS: Whether high intakes of fish and long-chain omega-3 polyunsaturated fatty acids (PUFAs) reduce the risk of atrial fibrillation (AF) remains uncertain. Thus, we aimed to evaluate the associations of total fish, types of fish, and omega-3 PUFA intake with AF incidence in a large prospective study.METHODS: We used data from the Cohort of Swedish Men and the Swedish Mammography Cohort to examine the associations of fish consumption and long-chain omega-3 PUFA intake with AF incidence. At baseline, information on fish and omega-3 PUFA intakes was available from 72,984 men and women, aged 45-83 years, without cardiac disease. Cases of AF were identified through linkage with the Swedish National Patient Register. Multivariable-adjusted relative risks were estimated with the use of Cox proportional hazards models.RESULTS: Over a follow-up period of 12 years, 6095 participants (3595 men and 2500 women) developed AF. Intakes of total fish, fatty fish (herring/mackerel and salmon/whitefish/char), and long-chain omega-3 PUFAs were not associated with AF incidence after adjustment for other risk factors. However, high consumption of lean fish (cod/saithe/fish fingers) was associated with a lower risk; multivariable relative risk of AF for ≥3 servings/week compared with never consumption was 0.79 (95% confidence interval, 0.65-0.95).CONCLUSIONS: These findings do not support a beneficial association of fatty fish or omega-3 PUFA intake with incident AF. The association between lean fish consumption and AF risk warrants further investigation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Nyckelord
- Atrial fibrillation
- Diet
- Fish
- Polyunsaturated fatty acids
- Prospective studies
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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