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Rapid Increase in C...
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden
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- Kaarme, Johan (författare)
- Uppsala universitet,Pediatrisk inflammationsforskning
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- Riedel, Hilde M. (författare)
- Uppsala universitet,Infektionsmedicin
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- Schaal, Wesley, PhD (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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Yin, Hong (författare)
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- Nevéus, Tryggve, 1965- (författare)
- Uppsala universitet,Pediatrisk inflammationsforskning
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- Melhus, Åsa (författare)
- Uppsala universitet,Infektionsmedicin
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(creator_code:org_t)
- Centers for Disease Control and Prevention (CDC), 2018
- 2018
- Engelska.
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Ingår i: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6040 .- 1080-6059. ; 24:10, s. 1874-1881
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://wwwnc.cdc.go...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non-ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- AmpC
- ESBLs
- Enterobacteriaceae
- Sweden
- antimicrobial resistance
- bacteria
- carriage rates
- cephalosporin resistance
- enteric infections
- extended-spectrum β-lactamases
- healthy preschool children
- preschool children
- respiratory infections
- whole-genome sequencing
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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