The first example of a Hoogsteen basepaired DNA duplex in dynamic equilibrium with a Watson-Crick basepaired duplex - A structural (NMR), kinetic and thermodynamic study

• A single-point substitution of the O4' oxygen by a CH2 group at the sugar residue of (A) under bar (6) (i.e. 2'-deoxyaristeromycin moiety) in a self-complementary DNA duplex, 5'd-(C(1)G(2)C(3)G(4)A(5)A(6)T(7)T(8)C(9)G(10)C(11)G(12))(2)(-3,), has been show

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NUCLEIC-ACID; PSEUDOROTATIONAL EQUILIBRIUM; PENTOFURANOSE MOIETY; MOLECULAR-DYNAMICS; CIRCULAR-DICHROISM; SUGAR CONFORMATION; COUPLING-CONSTANTS; P-31 NMR; A-DNA; NUCLEOSIDES

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