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Exogenous female se...
Exogenous female sex steroids may reduce lung ageing after menopause : A 20-year follow-up study of a general population sample (ECRHS)
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- Triebner, Kai (författare)
- Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway
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- Accordini, Simone (författare)
- Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Inst Biol 2, Str Le Grazie 8, I-37134 Verona, Italy
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- Calciano, Lucia (författare)
- Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Inst Biol 2, Str Le Grazie 8, I-37134 Verona, Italy
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- Johannessen, Ane (författare)
- Haukeland Hosp, Dept Occupat Med, Jonas Lies Vei 65, N-5021 Bergen, Norway;Univ Bergen, Ctr Int Hlth, Jekteviksbakken 31, N-5009 Bergen, Norway
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- Benediktsdottir, Bryndis (författare)
- Univ Iceland, Fac Med, Reykjavik, Iceland
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- Bifulco, Ersilia (författare)
- Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway
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- Demoly, Pascal (författare)
- Univ Montpellier, Univ Hosp Montpellier, Dept Pulmonol, Div Allergy, 371 Ave Doyen Gaston Giraud, F-34295 Montpellier, France;Sorbonne Univ, French Natl Inst Hlth & Med Res, Pierre Louis Inst Epidemiol & Publ Hlth, 56 Blvd Vincent Auriol, F-75646 Paris, France
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- Dharmage, Shyamali C. (författare)
- Univ Melbourne, Melbourne Sch Populat & Global Hlth, Allergy & Lung Hlth Unit, 207 Bouverie St, Carlton, Vic 3052, Australia
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- Franklin, Karl A. (författare)
- Umeå universitet,Kirurgi,Umea Univ, Dept Surg & Perioperat Sci, Koksvagen 11, S-90185 Umea, Sweden
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- Garcia-Aymerich, Judith (författare)
- ISGlobal, Doctor Aiguader 88, Barcelona 08003, Spain;Univ Pompeu Fabra, Doctor Aiguader 88, Barcelona 08003, Spain;CIBER Epidemiol & Publ Hlth, Doctor Aiguader 88, Barcelona 08003, Spain
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- Gullon Blanco, Jose Antonio (författare)
- Univ Hosp San Agustin, Dept Pneumol, Camino Heros 4, Aviles 33410, Spain
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- Heinrich, Joachim (författare)
- Ludwig Maximilian Univ Munich, Inst & Outpatient Clin Occupat Social & Environm, Ziemssenstr 1, D-80336 Munich, Germany
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- Holm, Mathias, 1969 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine
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- Jarvis, Debbie (författare)
- Imperial Coll, Natl Heart & Lung Inst, 1b Manresa Rd, London SW3 6LR, England
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- Jogi, Rain (författare)
- Uppsala universitet,Lung- allergi- och sömnforskning,Tartu Univ Hosp, Lung Clin, Dept Lung Med, Riia 167, EE-51014 Tartu, Estonia
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- Lindberg, Eva (författare)
- Uppsala universitet,Lung- allergi- och sömnforskning
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- Martinez-Moratalla, Jesus (författare)
- Hlth Serv Castilla La Mancha, Pulmonol Serv, Albacete Univ Hosp Complex, Albacete, Spain;Castilla La Mancha Univ, Fac Med Albacete, Albacete, Spain
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- Muniozguren Agirre, Nerea (författare)
- Basque Govt, Dept Hlth, Unit Epidemiol & Publ Hlth, Alameda Rekalde 39A, Bilbao 48008, Spain
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- Pin, Isabelle (författare)
- Univ Grenoble Alpes, Univ Hosp Grenoble Alpes, French Natl Inst Hlth & Med Res, Inst Adv Biosci,Dept Pediat, CS 10217, F-38043 Grenoble 9, France
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- Probst-Hensch, Nicole (författare)
- Swiss Trop & Publ Hlth Inst, Socinstr 58, CH-4002 Basel, Switzerland;Univ Basel, Dept Publ Hlth, Peterspl 1, CH-4001 Basel, Switzerland
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- Raherison, Chantal (författare)
- Bordeaux Univ, Bordeaux Populat Hlth Res, U1219, 146 Rue Leo Saignat, F-33076 Bordeaux, France
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- Luis Sanchez-Ramos, Jose (författare)
- Univ Huelva, Dept Nursing, Ave Tres Marzo S-N, Huelva 21071, Spain
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- Schlunssen, Vivi (författare)
- Aarhus Univ, Dept Publ Hlth, Bartholins Alle 2, DK-8000 Aarhus, Denmark;Natl Res Ctr Working Environm, Lerso Pk Alle 105, DK-2100 Copenhagen, Denmark
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- Svanes, Cecilie (författare)
- Haukeland Hosp, Dept Occupat Med, Jonas Lies Vei 65, N-5021 Bergen, Norway;Univ Bergen, Ctr Int Hlth, Jekteviksbakken 31, N-5009 Bergen, Norway
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- Hustad, Steinar (författare)
- Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Univ Bergen, Core Facil Metabol, Jonas Lies Veg 87, N-5021 Bergen, Norway
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- Leynaert, Benedicte (författare)
- French Natl Inst Hlth & Med Res, UMR1152, Team Epidemiol, Paris, France
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- Real, Francisco Gomez (författare)
- Univ Bergen, Dept Clin Sci, Jonas Lies Veg 87, N-5021 Bergen, Norway;Haukeland Hosp, Dept Gynecol & Obstet, Jonas Lies Veg 65, N-5021 Bergen, Norway
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(creator_code:org_t)
- ELSEVIER IRELAND LTD, 2019
- 2019
- Engelska.
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Ingår i: Maturitas. - : ELSEVIER IRELAND LTD. - 0378-5122 .- 1873-4111. ; 120, s. 29-34
- Relaterad länk:
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https://uu.diva-port... (primary) (Raw object)
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https://www.maturita...
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The effects of HRT on lung function decline, hence lung ageing, have not yet been investigated despite the recognized effects of HRT on other health outcomes. Study design: The population-based multi-centre European Community Respiratory Health Survey provided complete data for 275 oral HRT users at two time points, who were matched with 383 nonusers and analysed with a two-level linear mixed effects regression model. Main outcome measures: We studied whether HRT use was associated with the annual decline in forced vital capacity (FVC) and forced expiratory volume in one second (FEV1). Results: Lung function of women using oral HRT for more than five years declined less rapidly than that of nonusers. The adjusted difference in FVC decline was 5.6 mL/y (95%CI: 1.8 to 9.3, p = 0.01) for women who had taken HRT for six to ten years and 8.9 mL/y (3.5 to 14.2, p = 0.003) for those who had taken it for more than ten years. The adjusted difference in FEV1 decline was 4.4 mL/y (0.9 to 8.0, p = 0.02) with treatment from six to ten years and 5.3 mL/y (0.4 to 10.2, p = 0.048) with treatment for over ten years. Conclusions: In this longitudinal population-based study, the decline in lung function was less rapid in women who used HRT, following a dose-response pattern, and consistent when adjusting for potential confounding factors. This may signify that female sex hormones are of importance for lung ageing.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Hormone replacement therapy (HRT)
- Lung function
- Menopause
- Reproductive aging
- Sex hormones
- Hormone replacement therapy (HRT)
- Lung function
- Menopause
- Reproductive aging
- Sex hormones
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Triebner, Kai
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Accordini, Simon ...
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Calciano, Lucia
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Johannessen, Ane
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Benediktsdottir, ...
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Bifulco, Ersilia
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visa fler...
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Demoly, Pascal
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Dharmage, Shyama ...
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Franklin, Karl A ...
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Garcia-Aymerich, ...
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Gullon Blanco, J ...
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Heinrich, Joachi ...
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Holm, Mathias, 1 ...
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Jarvis, Debbie
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Jogi, Rain
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Lindberg, Eva
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Martinez-Moratal ...
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Muniozguren Agir ...
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Pin, Isabelle
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Probst-Hensch, N ...
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Raherison, Chant ...
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Luis Sanchez-Ram ...
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Schlunssen, Vivi
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Svanes, Cecilie
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Hustad, Steinar
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Leynaert, Benedi ...
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Real, Francisco ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Reproduktionsmed ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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