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Implications of seq...
Implications of sequence variation on the evolution of rRNA
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- Parks, Matthew M. (författare)
- Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA
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- Kurylo, Chad M. (författare)
- Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA
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- Batchelder, Jake E. (författare)
- Weill Cornell Med, Dept Immunol, New York, NY USA
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- Vincent, C. Theresa (författare)
- Uppsala universitet,Neuroonkologi,Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA
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- Blanchard, Scott C. (författare)
- Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA;Weill Cornell Med, Triinst PhD Program Chem Biol, New York, NY 10065 USA
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(creator_code:org_t)
- 2019-02-05
- 2019
- Engelska.
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Ingår i: Chromosome Research. - : Springer. - 0967-3849 .- 1573-6849. ; 27:1-2, s. 89-93
- Relaterad länk:
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https://link.springe...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The evolution of the multi-copy family of ribosomal RNA (rRNA) genes is unique in regard to its genetics and genome evolution. Paradoxically, rRNA genes are highly homogenized within and between individuals, yet they are globally distinct between species. Here, we discuss the implications for models of rRNA gene evolution in light of our recent discoveries that ribosomes bearing rRNA sequence variants can affect gene expression and physiology and that intra-individual rRNA alleles exhibit both context- and tissue-specific expression.
Ämnesord
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Nyckelord
- concerted evolution
- ribosomal RNA
- protein synthesis
- specialized ribosomes
- rDNA
- rRNA
- genome evolution
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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