Sökning: onr:"swepub:oai:DiVA.org:uu-405961" >
New light shed on t...
New light shed on the early evolution of limb-bone growth plate and bone marrow
-
- Lopez, Jordi Estefa (författare)
- Uppsala universitet,Evolution och utvecklingsbiologi
-
- Tafforeau, Paul (författare)
- European Synchrotron Radiat Facil, Grenoble, France
-
- Clement, Alice (författare)
- Flinders Univ S Australia, Coll Sci & Engn, Adelaide, SA, Australia
-
visa fler...
-
- Klembara, Jozef (författare)
- Comenius Univ, Fac Nat Sci, Dept Ecol, Bratislava, Slovakia
-
- Niedzwiedzki, Grzegorz, 1980- (författare)
- Uppsala universitet,Evolution och utvecklingsbiologi
-
- Berruyer, Camille (författare)
- European Synchrotron Radiat Facil, Grenoble, France
-
- Sanchez, Sophie (författare)
- Uppsala universitet,Evolution och utvecklingsbiologi,European Synchrotron Radiat Facil, Grenoble, France
-
visa färre...
-
(creator_code:org_t)
- eLife Sciences Publications Ltd, 2021
- 2021
- Engelska.
-
Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 10
- Relaterad länk:
-
https://doi.org/10.7...
-
visa fler...
-
https://uu.diva-port... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.7...
-
visa färre...
Abstract
Ämnesord
Stäng
- The production of blood cells (haematopoiesis) occurs in the limb bones of most tetrapods but is absent from the fin bones of ray-finned fish. When did long bones start producing blood cells? Recent hypotheses suggested that haematopoiesis migrated into long bones prior to the water-to-land transition and protected newly-produced blood cells from harsher environmental conditions. However little fossil evidence to support these hypotheses has been provided so far. Observations of the humeral microarchitecture of stem-tetrapods, batrachians and amniotes were performed using classical sectioning and three-dimensional synchrotron virtual histology. They show that Permian tetrapods seem to be among the first to exhibit a centralised marrow organisation which allows haematopoiesis as in extant amniotes. Not only does our study demonstrate that long-bone haematopoiesis was probably not an exaptation to the water-to-land transition but it sheds light on the early evolution of limb-bone development and the sequence of bone-marrow functional acquisitions.
Ämnesord
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Nyckelord
- three-dimensional virtual palaeohistology
- tetrapod terrestrialisation
- haematopoiesis
- amphibians
- stem amniotes
- Permian
- propagation phase-contrast synchrotron microtomography.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
-
eLIFE
(Sök värdpublikationen i LIBRIS)
Till lärosätets databas