SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:uu-408792"
 

Sökning: onr:"swepub:oai:DiVA.org:uu-408792" > Evidence for eosino...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004173naa a2200469 4500
001oai:DiVA.org:uu-408792
003SwePub
008200414s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4087922 URI
0247 a https://doi.org/10.1186/s12948-020-00117-62 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Amin, Kawau Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut0 (Swepub:uu)kawaamin
2451 0a Evidence for eosinophil and IL-17 mediated inflammation in allergic rhinitis
264 c 2020-04-04
264 1b Springer Science and Business Media LLC,c 2020
338 a electronic2 rdacarrier
520 a Background: The aim was to determine the level of inflammatory cytokines, eosinophil cationic protein and IgE in allergic rhinitis (AR) patients.Subjects and methods: Blood samples were taken from 88 AR patients and 88 healthy controls (HC). Each sample was analysed for eosinophil counts by flow cytometry, IgE by ECLIA, ECP, IL-17, and IL-33 by using ELISA test.Results: There was no significant difference between AR patients and the control group in age and gender. Levels of eosinophils, IgE, ECP, IL-17, IL-33 and the total symptom scores were significantly higher in AR patients than the HC (P = 0.0001). Serum ECP correlated with IL-17 (P = 0.041, r = 0.42), IL-33 (P = 0.0001, r = 080), and IgE levels (P = 0.017, r = 0.45) in the R patients. There was no correlation between IL-17 and IL-33. There was a correlation between symptom scores and eosinophils (P = 0.026, r = 0.52), and IgE (P = 0.001, r = 0.60) in the patients. No correlation was observed between symptom scores and ECP, IL-17, and IL-33 in the AR patient.Conclusions: Patients with AR have significant higher serum levels of ECP, IL-17, and IL-33 than healthy controls. This indicates that these markers could be used to in order to diagnose AR and to monitor disease. Inhibitory molecules to IL-17 and IL-33 may be considered as novel treatment strategies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
653 a Allergic rhinitis
653 a ECP
653 a IL-17
653 a IL-33
653 a IgE
653 a Immune system
7001 a Issa, Sulaf Mosau Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut
7001 a Ali, Kosar Mohammadu Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut
7001 a Aziz, Muaid Ismielu Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut
7001 a Hama Amieen, Huner Mohamedu Otolaryngology Center, Sulaimani Teaching Hospital, Sulaimanyah, Iraq4 aut
7001 a Byström, Jonasu Expermiental Medicine and Rheumatology, William Harvey Research Institute, Barts & The London, Queen Mary, University of London, Charterhouse Square, London, EC1M 6BQ, UK4 aut
7001 a Janson, Christeru Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)chrisjn
7102 a Uppsala universitetb Lung- allergi- och sömnforskning4 org
7730 t Clinical and Molecular Allergyd : Springer Science and Business Media LLCg 18q 18x 1476-7961
8564 u https://doi.org/10.1186/s12948-020-00117-6y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1423199/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://clinicalmolecularallergy.biomedcentral.com/track/pdf/10.1186/s12948-020-00117-6
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408792
8564 8u https://doi.org/10.1186/s12948-020-00117-6

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy