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Risk of Postoperati...
Risk of Postoperative Up Staging or Upgrading among Men with Low Risk Familial Prostate Cancer
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- Jansson, Fredrik (författare)
- Karolinska Institutet
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- Folkvaljon, Folke (författare)
- Uppsala universitet,Urologkirurgi
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- Stattin, Pär (författare)
- Uppsala universitet,Urologkirurgi
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- Bratt, Ola (författare)
- Univ Gothenburg, Dept Urol, Inst Clin Sci, Sahlgrenska Acad, Gothenburg, Sweden.
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- Akre, Olof (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2020
- 2020
- Engelska.
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Ingår i: Journal of Urology. - 0022-5347 .- 1527-3792. ; 204:1, s. 79-81
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Purpose: We investigated whether men with biopsy verified, low grade cancer and a family history of lethal or advanced prostate cancer are at particularly high risk for harboring undetected high grade disease.Materials and Methods: Upgrading and up staging of prostate cancer are common after prostatectomy. In a nationwide population based cohort we identified 6,854 men with low risk prostate cancer who underwent radical prostatectomy. Among these men 1,739 (25%) had a history of prostate cancer in a first-degree relative and 289 (4%) had a first-degree relative with lethal or advanced prostate cancer.Results: Compared to men with no familial occurrence of prostate cancer, the odds ratio for the risk of up staging among men with a familial occurrence of high risk or lethal prostate cancer was 1.06 (95% CI 0.76-1.47). The corresponding odds ratio for upgrading was 1.17 (0.91-1.50).Conclusions: We found no association between family history of prostate cancer and up staging or upgrading after radical prostatectomy.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- prostatic neoplasms
- neoplasm grading
- neoplasm staging
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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