Sökning: onr:"swepub:oai:DiVA.org:uu-421315" >
Physical activity a...
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Bedard, AnnabelleISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.
(författare)
Physical activity and lung function-Cause or consequence?
- Artikel/kapitelEngelska2020
Förlag, utgivningsår, omfång ...
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2020-08-20
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PUBLIC LIBRARY SCIENCE,2020
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-421315
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-421315URI
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https://doi.org/10.1371/journal.pone.0237769DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied structural equation modeling (SEM), an exploratory approach, and marginal structural modeling (MSM), an approach from the causal inference framework that corrects for reverse causation and time-dependent confounding and estimates causal effects, on data from participants in the European Community Respiratory Health Survey (ECRHS, a multicentre European cohort study initiated in 1991-1993 with ECRHS I, and with two follow-ups: ECRHS II in 1999-2003, and ECRHS III in 2010-2014). 753 subjects who reported current smoking at ECRHS II, with repeated data on lung function at ECRHS I, II and III, physical activity at ECRHS II and III, and potential confounders at ECRHS I and II, were included in the analyses. SEM showed positive associations between physical activity and lung function in both directions. MSM suggested a protectivecausaleffect of physical activity on lung function (overall difference in mean beta (95% CI), comparing active versus non-active individuals: 58 mL (21-95) for forced expiratory volume in one second and 83 mL (36-130) for forced vital capacity). Our results suggest bi-directional causation and support a true protective effect of physical activity on lung function in smokers, after accounting for reverse causation and time-dependent confounding.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Carsin, Anne-ElieISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.
(författare)
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Fuertes, ElaineISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.;Imperial Coll London, Natl Heart & Lung Inst, London, England.
(författare)
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Accordini, SimoneUniv Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy.
(författare)
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Dharmage, Shyamali C.Univ Melbourne, Sch Populat & Global Hlth, Allergy & Lung Hlth Unit, Melbourne, Vic, Australia.
(författare)
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Garcia-Larsen, VanessaJohns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Program Human Nutr, Baltimore, MD USA.
(författare)
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Heinrich, JoachimUniv Melbourne, Sch Populat & Global Hlth, Allergy & Lung Hlth Unit, Melbourne, Vic, Australia.;Ludwig Maximilians Univ Munchen, Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany.
(författare)
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Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)chrisjn
(författare)
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Johannessen, AneUniv Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway.;Haukeland Hosp, Dept Occupat Med, Bergen, Norway.
(författare)
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Leynaert, BenedicteINSERM, Pathophysiol & Epidemiol Resp Dis, UMR 1152, Paris, France.;Univ Paris Diderot, UMR 1152, Paris, France.
(författare)
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Luis Sanchez-Ramos, JoseJuan Ramon Jimenez Hosp, Pneumol Serv, Huelva, Spain.
(författare)
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Peralta, Gabriela P.ISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.
(författare)
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Pin, IsabelleCHU Grenoble Alpes, Dept Pediat, Grenoble, France.;INSERM, Inst Adv Biosci, Grenoble, France.;Univ Grenoble Alpes, Grenoble, France.
(författare)
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Squillacioti, GiuliaUniv Turin, Dept Publ Hlth & Pediat, Turin, Italy.
(författare)
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Weyler, JoostUniv Antwerp, Dept Epidemiol & Social Med, Antwerp, Belgium.
(författare)
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Jarvis, DeborahImperial Coll London, Natl Heart & Lung Inst, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.
(författare)
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Garcia-Aymerich, JudithISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.
(författare)
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ISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.ISGlobal, Barcelona, Spain.;Univ Pompeu Fabra UPF, Barcelona, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain.;Imperial Coll London, Natl Heart & Lung Inst, London, England.
(creator_code:org_t)
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Ingår i:PLOS ONE: PUBLIC LIBRARY SCIENCE15:81932-6203
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Bedard, Annabell ...
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Carsin, Anne-Eli ...
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Fuertes, Elaine
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Accordini, Simon ...
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Dharmage, Shyama ...
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Garcia-Larsen, V ...
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visa fler...
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Heinrich, Joachi ...
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Janson, Christer
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Johannessen, Ane
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Leynaert, Benedi ...
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Luis Sanchez-Ram ...
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Peralta, Gabriel ...
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Pin, Isabelle
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Squillacioti, Gi ...
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Weyler, Joost
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Jarvis, Deborah
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Garcia-Aymerich, ...
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