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A Pooled Analysis o...
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Cerhan, James R.Mayo Clin, Div Epidemiol, Rochester, MN USA.
(författare)
A Pooled Analysis of Waist Circumference and Mortality in 650,000 Adults
- Artikel/kapitelEngelska2014
Förlag, utgivningsår, omfång ...
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ELSEVIER SCIENCE INC,2014
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-422014
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422014URI
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https://doi.org/10.1016/j.mayocp.2013.11.011DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:128701051URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Objectives: To assess the independent effect of waist circumference on mortality across the entire body mass index (BMI) range and to estimate the loss in life expectancy related to a higher waist circumference. Patients and Methods: We pooled data from 11 prospective cohort studies with 650,386 white adults aged 20 to 83 years and enrolled from January 1, 1986, through December 31, 2000. We used proportional hazards regression to estimate hazard ratios (HRs) and 95% CIs for the association of waist circumference with mortality. Results: During a median follow-up of 9 years (maximum, 21 years), 78,268 participants died. After accounting for age, study, BMI, smoking status, alcohol consumption, and physical activity, a strong positive linear association of waist circumference with all-cause mortality was observed for men (HR, 1.52 for waist circumferences of >= 110 vs < 90 cm; 95% CI, 1.45-1.59; HR, 1.07 per 5-cm increment in waist circumference; 95% CI, 1.06-1.08) and women (HR, 1.80 for waist circumferences of >= 95 vs < 70 cm; 95% CI, 1.70-1.89; HR, 1.09 per 5-cm increment in waist circumference; 95% CI, 1.08-1.09). The estimated decrease in life expectancy for highest vs lowest waist circumference was approximately 3 years for men and approximately 5 years for women. The HR per 5-cm increment in waist circumference was similar for both sexes at all BMI levels from 20 to 50 kg/m(2), but it was higher at younger ages, higher for longer follow-up, and lower among male current smokers. The associations were stronger for heart and respiratory disease mortality than for cancer. Conclusions: In white adults, higher waist circumference was positively associated with higher mortality at all levels of BMI from 20 to 50 kg/m(2). Waist circumference should be assessed in combination with BMI, even for those in the normal BMI range, as part of risk assessment for obesity-related premature mortality. (C) 2014 Mayo Foundation for Medical Education and Research
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Moore, Steven C.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Jacobs, Eric J.Amer Canc Soc, Res Program, Atlanta, GA 30329 USA.
(författare)
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Kitahara, Cari M.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Rosenberg, Philip S.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Adami, Hans-OlovKarolinska Institutet
(författare)
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Ebbert, Jon O.Mayo Clin, Div Primary Care Internal Med, Rochester, MN USA.
(författare)
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English, Dallas R.Univ Melbourne, MEGA Epidemiol, Melbourne, Vic, Australia.
(författare)
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Gapstur, Susan M.Amer Canc Soc, Res Program, Atlanta, GA 30329 USA.
(författare)
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Giles, Graham G.Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.
(författare)
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Horn-Ross, Pamela L.Canc Prevent Inst Calif, Fremont, CA 94538 USA.
(författare)
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Park, YikyungNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Patel, Alpa V.Amer Canc Soc, Res Program, Atlanta, GA 30329 USA.
(författare)
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Robien, KimUniv Minnesota, Sch Publ Hlth, Minneapolis, MN USA.
(författare)
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Weiderpass, ElisabeteKarolinska Institutet
(författare)
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Willett, Walter C.Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
(författare)
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Wolk, AlicjaKarolinska Institutet
(författare)
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Zeleniuch-Jacquotte, AnneNYU, Sch Med, Dept Populat Hlth, New York, NY USA.
(författare)
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Hartge, PatriciaNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Bernstein, LeslieCity Hope Natl Med Ctr, Duarte, CA USA.
(författare)
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de Gonzalez, Amy BerringtonNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Mayo Clin, Div Epidemiol, Rochester, MN USA.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Mayo Clinic proceedings: ELSEVIER SCIENCE INC89:3, s. 335-3450025-61961942-5546
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Cerhan, James R.
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Moore, Steven C.
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Jacobs, Eric J.
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Kitahara, Cari M ...
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Rosenberg, Phili ...
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Adami, Hans-Olov
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visa fler...
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Ebbert, Jon O.
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English, Dallas ...
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Gapstur, Susan M ...
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Giles, Graham G.
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Horn-Ross, Pamel ...
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Park, Yikyung
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Patel, Alpa V.
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Robien, Kim
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Weiderpass, Elis ...
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Willett, Walter ...
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Wolk, Alicja
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Zeleniuch-Jacquo ...
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Hartge, Patricia
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Bernstein, Lesli ...
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de Gonzalez, Amy ...
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