Sökning: onr:"swepub:oai:DiVA.org:uu-422064" >
Chocolate consumpti...
-
Larsson, Susanna C.Karolinska Institutet
(författare)
Chocolate consumption and risk of stroke A prospective cohort of men and meta-analysis
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
-
LIPPINCOTT WILLIAMS & WILKINS,2012
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:uu-422064
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422064URI
-
https://doi.org/10.1212/WNL.0b013e31826aacfaDOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:125343110URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Objective: To investigate the association between chocolate consumption and risk of stroke in men and conduct a meta-analysis to summarize available evidence from prospective studies of chocolate consumption and stroke. Methods: We prospectively followed 37,103 men in the Cohort of Swedish Men. Chocolate consumption was assessed at baseline using a food-frequency questionnaire. Cases of first stroke were ascertained from the Swedish Hospital Discharge Registry. For the meta-analysis, pertinent studies were identified by searching the PubMed and EMBASE databases through January 13, 2012. Study-specific results were combined using a random-effects model. Results: During 10.2 years of follow-up, we ascertained 1,995 incident stroke cases, including 1,511 cerebral infarctions, 321 hemorrhagic strokes, and 163 unspecified strokes. High chocolate consumption was associated with a lower risk of stroke. The multivariable relative risk of stroke comparing the highest quartile of chocolate consumption (median 62.9 g/week) with the lowest quartile (median 0 g/week) was 0.83 (95% CI 0.70-0.99). The association did not differ by stroke subtypes. In a meta-analysis of 5 studies, with a total of 4,260 stroke cases, the overall relative risk of stroke for the highest vs lowest category of chocolate consumption was 0.81 (95% CI 0.73-0.90), without heterogeneity among studies (p = 0.47). Conclusion: These findings suggest that moderate chocolate consumption may lower the risk of stroke. Neurology (R) 2012;79:1223-1229
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Virtamo, JarmoNatl Inst Hlth & Welf, Dept Chron Dis Prevent, Helsinki, Finland.
(författare)
-
Wolk, AlicjaKarolinska Institutet
(författare)
-
Karolinska InstitutetNatl Inst Hlth & Welf, Dept Chron Dis Prevent, Helsinki, Finland.
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Neurology: LIPPINCOTT WILLIAMS & WILKINS79:12, s. 1223-12290028-38781526-632X
Internetlänk
Hitta via bibliotek
Till lärosätets databas