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Sökning: onr:"swepub:oai:DiVA.org:uu-422096" > Body-Mass Index and...

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FältnamnIndikatorerMetadata
00006547naa a2200721 4500
001oai:DiVA.org:uu-422096
003SwePub
008201013s2010 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:121623389
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4220962 URI
024a https://doi.org/10.1056/NEJMoa10003672 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1216233892 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a de Gonzalez, Amy Berringtonu NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.4 aut
2451 0a Body-Mass Index and Mortality among 1.46 Million White Adults.
264 1b MASSACHUSETTS MEDICAL SOC,c 2010
338 a print2 rdacarrier
520 a Background: A high body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) is associated with increased mortality from cardiovascular disease and certain cancers, but the precise relationship between BMI and all-cause mortality remains uncertain. Methods: We used Cox regression to estimate hazard ratios and 95% confidence intervals for an association between BMI and all-cause mortality, adjusting for age, study, physical activity, alcohol consumption, education, and marital status in pooled data from 19 prospective studies encompassing 1.46 million white adults, 19 to 84 years of age (median, 58). Results: The median baseline BMI was 26.2. During a median follow-up period of 10 years (range, 5 to 28), 160,087 deaths were identified. Among healthy participants who never smoked, there was a J-shaped relationship between BMI and all-cause mortality. With a BMI of 22.5 to 24.9 as the reference category, hazard ratios among women were 1.47 (95 percent confidence interval [CI], 1.33 to 1.62) for a BMI of 15.0 to 18.4; 1.14 (95% CI, 1.07 to 1.22) for a BMI of 18.5 to 19.9; 1.00 (95% CI, 0.96 to 1.04) for a BMI of 20.0 to 22.4; 1.13 (95% CI, 1.09 to 1.17) for a BMI of 25.0 to 29.9; 1.44 (95% CI, 1.38 to 1.50) for a BMI of 30.0 to 34.9; 1.88 (95% CI, 1.77 to 2.00) for a BMI of 35.0 to 39.9; and 2.51 (95% CI, 2.30 to 2.73) for a BMI of 40.0 to 49.9. In general, the hazard ratios for the men were similar. Hazard ratios for a BMI below 20.0 were attenuated with longer-term follow-up. Conclusions: In white adults, overweight and obesity (and possibly underweight) are associated with increased all-cause mortality. All-cause mortality is generally lowest with a BMI of 20.0 to 24.9. N Engl J Med 2010;363:2211-9.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
700a Hartge, Patricia4 aut
700a Cerhan, James R.u Mayo Clin, Coll Med, Div Epidemiol, Rochester, MN USA.4 aut
700a Flint, Alan J.u Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.4 aut
700a Hannan, Lindsayu Amer Canc Soc, Dept Epidemiol & Surveillance Res, Atlanta, GA 30329 USA.4 aut
700a MacInnis, Robert J.u Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.;Univ Cambridge, Canc Res UK Genet Epidemiol Unit, Cambridge, England.4 aut
700a Moore, Steven C.4 aut
700a Tobias, Geoffrey S.4 aut
700a Anton-Culver, Hodau Univ Calif Irvine, Sch Med, Dept Epidemiol, Irvine, CA 92717 USA.4 aut
700a Freeman, Laura Beane4 aut
700a Beeson, W. Lawrenceu Loma Linda Univ, Sch Publ Hlth, Loma Linda, CA 92350 USA.4 aut
700a Clipp, Sandra L.u Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut
700a English, Dallas R.u Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.4 aut
700a Folsom, Aaron R.u Univ Minnesota, Sch Publ Hlth, Minneapolis, MN USA.4 aut
700a Freedman, D. Michal4 aut
700a Giles, Grahamu Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.4 aut
700a Hakansson, Niclasu Karolinska Institutet4 aut
700a Henderson, Katherine D.u City Hope Natl Med Ctr, Dept Populat Sci, Duarte, CA 91010 USA.4 aut
700a Hoffman-Bolton, Judithu Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut
700a Hoppin, Jane A.u Natl Inst Environm Hlth Sci, Epidemiol Branch, Res Triangle Pk, NC USA.4 aut
700a Koenig, Karen L.u NYU, Sch Med, Dept Environm Med, New York, NY USA.4 aut
700a Lee, I-Minu Harvard Univ, Sch Med, Boston, MA USA.4 aut
700a Linet, Martha S.4 aut
700a Park, Yikyung4 aut
700a Pocobelli, Gaiau Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA.;Fred Hutchinson Canc Res Ctr, Canc Prevent Program, Seattle, WA 98104 USA.4 aut
700a Schatzkin, Arthur4 aut
700a Sesso, Howard D.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.;Brigham & Womens Hosp, Div Aging, Boston, MA 02115 USA.4 aut
700a Weiderpass, Elisabeteu Karolinska Institutet4 aut
700a Willcox, Bradley J.u Pacific Hlth Res Inst, Honolulu, HI USA.;Queens Med Ctr, Honolulu, HI USA.4 aut
700a Wolk, Alicjau Karolinska Institutet4 aut
700a Zeleniuch-Jacquotte, Anneu NYU, Sch Med, Dept Environm Med, New York, NY USA.4 aut
700a Willett, Walter C.u Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.4 aut
700a Thun, Michael J.u Amer Canc Soc, Dept Epidemiol & Surveillance Res, Atlanta, GA 30329 USA.4 aut
710a NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.b Mayo Clin, Coll Med, Div Epidemiol, Rochester, MN USA.4 org
773t New England Journal of Medicined : MASSACHUSETTS MEDICAL SOCg 363:23, s. 2211-2219q 363:23<2211-2219x 0028-4793x 1533-4406
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422096
8564 8u https://doi.org/10.1056/NEJMoa1000367
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:121623389

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