Sökning: onr:"swepub:oai:DiVA.org:uu-422096" > Body-Mass Index and...
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000 | 06547naa a2200721 4500 | |
001 | oai:DiVA.org:uu-422096 | |
003 | SwePub | |
008 | 201013s2010 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:121623389 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4220962 URI |
024 | 7 | a https://doi.org/10.1056/NEJMoa10003672 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1216233892 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a de Gonzalez, Amy Berringtonu NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.4 aut |
245 | 1 0 | a Body-Mass Index and Mortality among 1.46 Million White Adults. |
264 | 1 | b MASSACHUSETTS MEDICAL SOC,c 2010 |
338 | a print2 rdacarrier | |
520 | a Background: A high body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) is associated with increased mortality from cardiovascular disease and certain cancers, but the precise relationship between BMI and all-cause mortality remains uncertain. Methods: We used Cox regression to estimate hazard ratios and 95% confidence intervals for an association between BMI and all-cause mortality, adjusting for age, study, physical activity, alcohol consumption, education, and marital status in pooled data from 19 prospective studies encompassing 1.46 million white adults, 19 to 84 years of age (median, 58). Results: The median baseline BMI was 26.2. During a median follow-up period of 10 years (range, 5 to 28), 160,087 deaths were identified. Among healthy participants who never smoked, there was a J-shaped relationship between BMI and all-cause mortality. With a BMI of 22.5 to 24.9 as the reference category, hazard ratios among women were 1.47 (95 percent confidence interval [CI], 1.33 to 1.62) for a BMI of 15.0 to 18.4; 1.14 (95% CI, 1.07 to 1.22) for a BMI of 18.5 to 19.9; 1.00 (95% CI, 0.96 to 1.04) for a BMI of 20.0 to 22.4; 1.13 (95% CI, 1.09 to 1.17) for a BMI of 25.0 to 29.9; 1.44 (95% CI, 1.38 to 1.50) for a BMI of 30.0 to 34.9; 1.88 (95% CI, 1.77 to 2.00) for a BMI of 35.0 to 39.9; and 2.51 (95% CI, 2.30 to 2.73) for a BMI of 40.0 to 49.9. In general, the hazard ratios for the men were similar. Hazard ratios for a BMI below 20.0 were attenuated with longer-term follow-up. Conclusions: In white adults, overweight and obesity (and possibly underweight) are associated with increased all-cause mortality. All-cause mortality is generally lowest with a BMI of 20.0 to 24.9. N Engl J Med 2010;363:2211-9. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
700 | 1 | a Hartge, Patricia4 aut |
700 | 1 | a Cerhan, James R.u Mayo Clin, Coll Med, Div Epidemiol, Rochester, MN USA.4 aut |
700 | 1 | a Flint, Alan J.u Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.4 aut |
700 | 1 | a Hannan, Lindsayu Amer Canc Soc, Dept Epidemiol & Surveillance Res, Atlanta, GA 30329 USA.4 aut |
700 | 1 | a MacInnis, Robert J.u Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.;Univ Cambridge, Canc Res UK Genet Epidemiol Unit, Cambridge, England.4 aut |
700 | 1 | a Moore, Steven C.4 aut |
700 | 1 | a Tobias, Geoffrey S.4 aut |
700 | 1 | a Anton-Culver, Hodau Univ Calif Irvine, Sch Med, Dept Epidemiol, Irvine, CA 92717 USA.4 aut |
700 | 1 | a Freeman, Laura Beane4 aut |
700 | 1 | a Beeson, W. Lawrenceu Loma Linda Univ, Sch Publ Hlth, Loma Linda, CA 92350 USA.4 aut |
700 | 1 | a Clipp, Sandra L.u Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut |
700 | 1 | a English, Dallas R.u Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.4 aut |
700 | 1 | a Folsom, Aaron R.u Univ Minnesota, Sch Publ Hlth, Minneapolis, MN USA.4 aut |
700 | 1 | a Freedman, D. Michal4 aut |
700 | 1 | a Giles, Grahamu Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.4 aut |
700 | 1 | a Hakansson, Niclasu Karolinska Institutet4 aut |
700 | 1 | a Henderson, Katherine D.u City Hope Natl Med Ctr, Dept Populat Sci, Duarte, CA 91010 USA.4 aut |
700 | 1 | a Hoffman-Bolton, Judithu Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.4 aut |
700 | 1 | a Hoppin, Jane A.u Natl Inst Environm Hlth Sci, Epidemiol Branch, Res Triangle Pk, NC USA.4 aut |
700 | 1 | a Koenig, Karen L.u NYU, Sch Med, Dept Environm Med, New York, NY USA.4 aut |
700 | 1 | a Lee, I-Minu Harvard Univ, Sch Med, Boston, MA USA.4 aut |
700 | 1 | a Linet, Martha S.4 aut |
700 | 1 | a Park, Yikyung4 aut |
700 | 1 | a Pocobelli, Gaiau Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA.;Fred Hutchinson Canc Res Ctr, Canc Prevent Program, Seattle, WA 98104 USA.4 aut |
700 | 1 | a Schatzkin, Arthur4 aut |
700 | 1 | a Sesso, Howard D.u Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.;Brigham & Womens Hosp, Div Aging, Boston, MA 02115 USA.4 aut |
700 | 1 | a Weiderpass, Elisabeteu Karolinska Institutet4 aut |
700 | 1 | a Willcox, Bradley J.u Pacific Hlth Res Inst, Honolulu, HI USA.;Queens Med Ctr, Honolulu, HI USA.4 aut |
700 | 1 | a Wolk, Alicjau Karolinska Institutet4 aut |
700 | 1 | a Zeleniuch-Jacquotte, Anneu NYU, Sch Med, Dept Environm Med, New York, NY USA.4 aut |
700 | 1 | a Willett, Walter C.u Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.4 aut |
700 | 1 | a Thun, Michael J.u Amer Canc Soc, Dept Epidemiol & Surveillance Res, Atlanta, GA 30329 USA.4 aut |
710 | 2 | a NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.b Mayo Clin, Coll Med, Div Epidemiol, Rochester, MN USA.4 org |
773 | 0 | t New England Journal of Medicined : MASSACHUSETTS MEDICAL SOCg 363:23, s. 2211-2219q 363:23<2211-2219x 0028-4793x 1533-4406 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422096 |
856 | 4 8 | u https://doi.org/10.1056/NEJMoa1000367 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:121623389 |
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