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Height, body mass i...
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Schouten, Leo J.Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands.
(författare)
Height, body mass index, and ovarian cancer : A pooled analysis of 12 cohort studies
- Artikel/kapitelEngelska2008
Förlag, utgivningsår, omfång ...
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AMER ASSOC CANCER RESEARCH,2008
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-422126
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422126URI
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https://doi.org/10.1158/1055-9965.EPI-07-2524DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:116873236URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Background: Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent. Methods: The associations of height, body mass index (BMI), and ovarian cancer risk were examined in a pooled analysis of primary data from 12 prospective cohort studies from North America and Europe. The study population consisted of 531,583 women among whom 2,036 epithelial ovarian cancer cases were identified. To summarize associations, study-specific relative risks (RR) were estimated using the Cox proportional hazards model and then combined using a random-effects model. Results: Women with height >= 1.70 m had a pooled multivariate RR of 1.38 [95% confidence interval (95% CI), 1.16-1-65] compared with those with height <1.60 m. For the same comparison, multivariate RRs were 1.79 (95% CI, 1.07-3.00) for premenopausal and 1.25 (95% CI, 1.04-1.49) for postmenopausal ovarian cancer (P(interaction) = 0.14). The multivariate RR for women with a BMI >= 30 kg/m(2) was 1.03 (95% CI, 0.86-1.22) compared with women with a BMI from 18.5 to 23 kg/m(2). For the same comparison, multivariate RRs were 1.72 (95% CI, 1.02-2.89) for premenopausal and 1.07 (95% CI, 0.87-1.33) for postmenopausal women (P(interaction) = 0.07). There was no statistically significant heterogeneity between studies with respect to height or BMI. BMI in early adulthood was not associated with ovarian cancer risk. Conclusion: Height was associated with an increased ovarian cancer risk, especially in premenopausal women. BMI was not associated with ovarian cancer risk in postmenopausal women but was positively associated with risk in premenopausal women.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Rivera, ChristineHarvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.
(författare)
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Hunter, David J.Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA.
(författare)
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Spiegelman, DonnaHarvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Biostat, Cambridge, MA 02138 USA.
(författare)
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Adami, Hans-OlovKarolinska Institutet
(författare)
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Arslan, AlanKarolinska Institutet
(författare)
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Beeson, W. LawrenceLoma Linda Univ, Sch Med, Ctr Hlth Res, Loma Linda, CA USA.
(författare)
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van den Brandt, Piet A.Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands.
(författare)
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Buring, Julie E.Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA.
(författare)
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Folsom, Aaron R.Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
(författare)
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Fraser, Gary E.Loma Linda Univ, Sch Med, Ctr Hlth Res, Loma Linda, CA USA.
(författare)
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Freudenheim, Jo L.SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY 14260 USA.
(författare)
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Goldbohm, R. AlexandraNetherlands Org Appl Sci Res Qual Life, Dept Food & Chem Risk Anal, Zeist, Netherlands.
(författare)
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Hankinson, Susan E.Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA.
(författare)
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Lacey, James V., Jr.NCI, NIH, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Leitzmann, MichaelNCI, NIH, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
(författare)
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Lukanova, Annekatrin
(författare)
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Marshall, James R.
(författare)
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Miller, Anthony B.Univ Toronto, Fac Med, Dept Publ Hlth Sci, Toronto, ON, Canada.
(författare)
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Patel, Alpa V.Amer Canc Soc, Atlanta, GA 30329 USA.
(författare)
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Rodriguez, CarmenAmer Canc Soc, Atlanta, GA 30329 USA.
(författare)
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Rohan, Thomas E.Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA.
(författare)
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Ross, Julie A.Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
(författare)
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Wolk, AlicjaKarolinska Inst, Dept Environm Med, Div Nutr Epidemiol, Stockholm, Sweden.
(författare)
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Zhang, Shumin M.Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA.
(författare)
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Smith-Warner, Stephanie A.Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.
(författare)
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Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands.Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Cancer Epidemiology, Biomarkers and Prevention: AMER ASSOC CANCER RESEARCH17:4, s. 902-9121055-99651538-7755
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Till lärosätets databas
- Av författaren/redakt...
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Schouten, Leo J.
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Rivera, Christin ...
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Hunter, David J.
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Spiegelman, Donn ...
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Adami, Hans-Olov
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Arslan, Alan
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visa fler...
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Beeson, W. Lawre ...
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van den Brandt, ...
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Buring, Julie E.
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Folsom, Aaron R.
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Fraser, Gary E.
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Freudenheim, Jo ...
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Goldbohm, R. Ale ...
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Hankinson, Susan ...
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Lacey, James V., ...
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Leitzmann, Micha ...
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Lukanova, Anneka ...
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Marshall, James ...
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Miller, Anthony ...
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Patel, Alpa V.
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Rodriguez, Carme ...
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Rohan, Thomas E.
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Ross, Julie A.
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Wolk, Alicja
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Zhang, Shumin M.
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Smith-Warner, St ...
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visa färre...
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