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Sökning: onr:"swepub:oai:DiVA.org:uu-423935" > Prevalence of sarco...

  • Moreno-Gonzalez, RafaelInst Invest Biomed Bellvitge IDIBELL, Hosp Univ Bellvitge, Cardiovasc Resp & Syst Dis & Cellular Aging Progr, Geriatr Unit,Internal Med Dept,Syst Dis & Ageing, Barcelona, Spain. (författare)

Prevalence of sarcopenia in community-dwelling older adults using the updated EWGSOP2 definition according to kidney function and albuminuria The Screening for CKD among Older People across Europe (SCOPE) study

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • 2020-10-02
  • BMC,2020
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-423935
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423935URI
  • https://doi.org/10.1186/s12877-020-01700-xDOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:du-35199URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:144883710URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background Loss of muscle mass and function may be more pronounced in older adults with chronic kidney disease (CKD) and with albuminuria. Thus, we investigated the prevalence of sarcopenia among community-dwelling older adults according to kidney function and grade of albuminuria. We also explored differences in the prevalence of sarcopenia according to three different equations for the estimation of glomerular filtration rate (eGFR). Methods A cross-sectional analysis of 1420 community-dwelling older adults (>= 75 years old) included in the SCOPE study, a multicenter prospective cohort study, was conducted. Comprehensive geriatric assessment including short physical performance battery (SPPB), handgrip strength test and bioelectrical impedance analysis (BIA) was performed. Sarcopenia was defined using the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). eGFR was calculated using Berlin Initiative Study (BIS), Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) and Full Age Spectrum (FAS) equations, and urinary albumin-to-creatinine ratio (ACR) was collected to categorize CKD according to Kidney Disease Improving Global Outcomes guidelines. Results Median age was 79.5 years (77.0-83.0), 804 (56.6%) were women. Using EWGSOP2 definition, 150 (10.6%) participants met diagnostic criteria for sarcopenia. Moreover, 85 (6%) participants had severe sarcopenia. Sarcopenia was more prevalent in participants with more advanced stages of CKD according to BIS eq. (9.6% in stages 1 and 2 and 13.9% in stages 3a, 3b and 4,p = 0.042), and also according to CKD-EPI (9.8% vs. 14.2%, p = 0.042) and FAS although not reaching statistical signification (9.8% vs. 12.7%,p = 0.119). Thus, differences in prevalence are observed among CKD categories as estimated by different equations. Prevalence of sarcopenia was also higher with increasing albuminuria categories: 9.3% in normoalbuminuric, 13.2% in microalbuminuric and 16.8% in macroalbuminuric participants, (p = 0.019). Conclusions Sarcopenia is common among community-dwelling older adults, especially among those with more advanced CKD categories, with prevalence estimates differing slightly depending on the equation used for the estimation of eGFR; as well as among those with higher albuminuria categories.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Corbella, XavierInst Invest Biomed Bellvitge IDIBELL, Hosp Univ Bellvitge, Cardiovasc Resp & Syst Dis & Cellular Aging Progr, Geriatr Unit,Internal Med Dept,Syst Dis & Ageing, Barcelona, Spain.;Catalunya Int Univ, Hestia Chair Integrated Hlth & Social Care, Fac Med & Hlth Sci, Barcelona, Spain. (författare)
  • Mattace-Raso, FrancescoErasmus MC, Univ Med Ctr Rotterdam, Geriatr Med Sect, Dept Internal Med, Rotterdam, Netherlands. (författare)
  • Tap, LisanneErasmus MC, Univ Med Ctr Rotterdam, Geriatr Med Sect, Dept Internal Med, Rotterdam, Netherlands. (författare)
  • Sieber, CornelFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging IBA, Nurnberg, Germany. (författare)
  • Freiberger, EllenFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging IBA, Nurnberg, Germany. (författare)
  • Kostka, TomaszMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (författare)
  • Guligowska, AgnieszkaMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (författare)
  • Melzer, ItshakBen Gurion Univ Negev, Dept Phys Therapy, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Beer Sheva, Israel. (författare)
  • Melzer, YehuditBen Gurion Univ Negev, Dept Phys Therapy, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Beer Sheva, Israel.;Maccabi Hlth Org, Tel Aviv, Israel. (författare)
  • Carlsson, Axel CKarolinska Institutet,Uppsala universitet,Institutionen för medicinska vetenskaper,Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden.(Swepub:uu)axeca883 (författare)
  • Ärnlöv, JohanKarolinska Institutet,Högskolan Dalarna,Uppsala universitet,Institutionen för medicinska vetenskaper,Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden.;Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.,Medicinsk vetenskap,Uppsala University; Karolinska Institutet(Swepub:du)jan (författare)
  • Roller-Wirnsberger, ReginaMed Univ Graz, Dept Internal Med, Graz, Austria. (författare)
  • Wirnsberger, GerhardMed Univ Graz, Dept Internal Med, Graz, Austria. (författare)
  • Gil, PedroHosp Clin San Carlos, Geriatr Dept, Martin Lagos S-N, Madrid 28040, Spain. (författare)
  • Martinez, Sara LainezHosp Clin San Carlos, Geriatr Dept, Martin Lagos S-N, Madrid 28040, Spain. (författare)
  • Fabbietti, PaoloIRCCS INRCA, Lab Geriatr Pharmacoepidemiol & Biostat, Via S Margherita 5, I-60124 Ancona, Italy. (författare)
  • Corsonello, AndreaIRCCS INRCA, Lab Geriatr Pharmacoepidemiol & Biostat, Via S Margherita 5, I-60124 Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Fermo, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Cosenza, Italy. (författare)
  • Lattanzio, FabriziaItalian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Fermo, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Cosenza, Italy. (författare)
  • Formiga, FrancescInst Invest Biomed Bellvitge IDIBELL, Hosp Univ Bellvitge, Cardiovasc Resp & Syst Dis & Cellular Aging Progr, Geriatr Unit,Internal Med Dept,Syst Dis & Ageing, Barcelona, Spain. (författare)
  • Inst Invest Biomed Bellvitge IDIBELL, Hosp Univ Bellvitge, Cardiovasc Resp & Syst Dis & Cellular Aging Progr, Geriatr Unit,Internal Med Dept,Syst Dis & Ageing, Barcelona, Spain.Inst Invest Biomed Bellvitge IDIBELL, Hosp Univ Bellvitge, Cardiovasc Resp & Syst Dis & Cellular Aging Progr, Geriatr Unit,Internal Med Dept,Syst Dis & Ageing, Barcelona, Spain.;Catalunya Int Univ, Hestia Chair Integrated Hlth & Social Care, Fac Med & Hlth Sci, Barcelona, Spain. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:BMC Geriatrics: BMC201471-2318

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