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Associations betwee...
Associations between respiratory infections and bacterial microbiome in student dormitories in Northern China.
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Fu, Xi (författare)
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Li, Yanling (författare)
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Meng, Yi (författare)
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Yuan, Qianqian (författare)
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Zhang, Zefei (författare)
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- Norbäck, Dan (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Arbets- och miljömedicin
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Deng, Yiqun (författare)
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Zhang, Xin (författare)
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Sun, Yu (författare)
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(creator_code:org_t)
- 2020-05
- 2020
- Engelska.
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Ingår i: Indoor Air. - : Hindawi Limited. - 0905-6947 .- 1600-0668. ; 30:5, s. 816-826
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Recent studies reveal that the microbial diversity and composition in the respiratory tract are related to the susceptibility, development, and progression of respiratory infections. Indoor microorganisms can transmit into the respiratory tract through breathing, but their role in infections is unclear. Here, we present the first association study between the indoor microbiome and respiratory infections. In total, 357 students living in 86 dormitory rooms in Shanxi University were randomly selected to survey symptoms of infections. Settled air dust was collected to characterize bacterial compositions by 16S rRNA sequencing. The overall microbial richness was not associated with respiratory infections, but microorganisms from specific phylogenetic classes showed various associations. Taxa richness and abundance of Actinobacteria were protectively associated with infections (P < .05). The abundance of several genera in Gammaproteobacteria, including Haemophilus, Klebsiella, Buttiauxella, and Raoultella, was positively associated with infections (P < .005). The role of these microorganisms was consistent with previous human microbiota studies. Building age was associated with the overall microbial composition variation in dormitories and negatively associated with three potential risk genera in Proteobacteria (P < .05). The weight of vacuum dust was positively associated with a protective genus, Micrococcus in Actinobacteria (P < .05).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- 16S rRNA sequencing
- Chinese university dormitories
- Gammaproteobacteria
- association analysis
- indoor microbiome
- respiratory infection
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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