Sökning: onr:"swepub:oai:DiVA.org:uu-431966" > Moderators of the e...
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000 | 05560naa a2200781 4500 | |
001 | oai:DiVA.org:uu-431966 | |
003 | SwePub | |
008 | 210115s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:144540374 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4319662 URI |
024 | 7 | a https://doi.org/10.1002/pon.55222 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1445403742 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Abrahams, Harriët J. G.4 aut |
245 | 1 0 | a Moderators of the effect of psychosocial interventions on fatigue in women with breast cancer and men with prostate cancer :b Individual patient data meta-analyses |
264 | c 2020-09-03 | |
264 | 1 | b Wiley,c 2020 |
338 | a print2 rdacarrier | |
520 | a ObjectivePsychosocial interventions can reduce cancer‐related fatigue effectively. However, it is still unclear if intervention effects differ across subgroups of patients. These meta‐analyses aimed at evaluating moderator effects of (a) sociodemographic characteristics, (b) clinical characteristics, (c) baseline levels of fatigue and other symptoms, and (d) intervention‐related characteristics on the effect of psychosocial interventions on cancer‐related fatigue in patients with non‐metastatic breast and prostate cancer.MethodsData were retrieved from the Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS) consortium. Potential moderators were studied with meta‐analyses of pooled individual patient data from 14 randomized controlled trials through linear mixed‐effects models with interaction tests. The analyses were conducted separately in patients with breast (n = 1091) and prostate cancer (n = 1008).ResultsStatistically significant, small overall effects of psychosocial interventions on fatigue were found (breast cancer: β = −0.19 [95% confidence interval (95%CI) = −0.30; −0.08]; prostate cancer: β = −0.11 [95%CI = −0.21; −0.00]). In both patient groups, intervention effects did not differ significantly by sociodemographic or clinical characteristics, nor by baseline levels of fatigue or pain. For intervention‐related moderators (only tested among women with breast cancer), statistically significant larger effects were found for cognitive behavioral therapy as intervention strategy (β = −0.27 [95%CI = −0.40; −0.15]), fatigue‐specific interventions (β = −0.48 [95%CI = −0.79; −0.18]), and interventions that only targeted patients with clinically relevant fatigue (β = −0.85 [95%CI = −1.40; −0.30]).ConclusionsOur findings did not provide evidence that any selected demographic or clinical characteristic, or baseline levels of fatigue or pain, moderated effects of psychosocial interventions on fatigue. A specific focus on decreasing fatigue seems beneficial for patients with breast cancer with clinically relevant fatigue. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
653 | a breast cancer | |
653 | a cancer | |
653 | a fatigue | |
653 | a individual patient data meta-analysis | |
653 | a moderators | |
653 | a oncology | |
653 | a prostate cancer | |
653 | a psycho-oncology | |
653 | a psychosocial interventions | |
700 | 1 | a Knoop, Hans4 aut |
700 | 1 | a Schreurs, Maartje4 aut |
700 | 1 | a Aaronson, Neil K.4 aut |
700 | 1 | a Jacobsen, Paul B.4 aut |
700 | 1 | a Newton, Robert U.4 aut |
700 | 1 | a Courneya, Kerry S.4 aut |
700 | 1 | a Aitken, Joanne F.4 aut |
700 | 1 | a Arving, Ceciliau Uppsala universitet,Livsstil och rehabilitering vid långvarig sjukdom4 aut0 (Swepub:uu)ceciarvi |
700 | 1 | a Brandberg, Yvonneu Karolinska Institutet4 aut |
700 | 1 | a Chambers, Suzanne K.4 aut |
700 | 1 | a Gielissen, Marieke F. M.4 aut |
700 | 1 | a Glimelius, Bengtu Uppsala universitet,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)bengglim |
700 | 1 | a Goedendorp, Martine M.4 aut |
700 | 1 | a Graves, Kristi D.4 aut |
700 | 1 | a Heiney, Sue P.4 aut |
700 | 1 | a Horne, Rob4 aut |
700 | 1 | a Hunter, Myra S.4 aut |
700 | 1 | a Johansson, Birgitta,d 1959-u Uppsala universitet,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)birgjhs |
700 | 1 | a Northouse, Laurel L.4 aut |
700 | 1 | a Oldenburg, Hester S. A.4 aut |
700 | 1 | a Prins, Judith B.4 aut |
700 | 1 | a Savard, Josée4 aut |
700 | 1 | a van Beurden, Marc4 aut |
700 | 1 | a van den Berg, Sanne W.4 aut |
700 | 1 | a Verdonck-de Leeuw, Irma M.4 aut |
700 | 1 | a Buffart, Laurien M.4 aut |
710 | 2 | a Uppsala universitetb Livsstil och rehabilitering vid långvarig sjukdom4 org |
773 | 0 | t Psycho-Oncologyd : Wileyg 29:11, s. 1772-1785q 29:11<1772-1785x 1057-9249x 1099-1611 |
856 | 4 | u https://pure.rug.nl/ws/files/133866046/Moderators_of_the_effect_of_psychosocial_interventions_on_fatigue_in_women_with_breast_cancer_and_men_with_prostate_cancer.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-431966 |
856 | 4 8 | u https://doi.org/10.1002/pon.5522 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:144540374 |
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