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Learning of nature :
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Lagunas-Rangel, Francisco AlejandroMaster in Health Sciences, Graduate Studies Division, Faculty of Biological and Medical Sciences "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo, Av. Rafael Carrillo without number, corner with Dr. Salvador González Herrejón, Bosque Cuauhtémoc, 58020, Morelia, Michoacán, Mexico
(författare)
Learning of nature : The curious case of the naked mole rat
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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Elsevier BV,2017
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-444521
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-444521URI
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https://doi.org/10.1016/j.mad.2017.04.010DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Naked mole rats (NMRs) are the longest-living rodents known, living up to approximately 30 years and showing sustained good health. Nowadays, NMRs are considered excellent models for aging and, additionally, for cancer research, due to the evidence of a remarkable cancer resistance demonstrated through thousands of necropsies performed with very few cases that describe this pathology, which is believed to be a disease that unavoidably accompanies aging. Since some years ago, several studies have tried to explain the possible mechanisms underlying longevity and cancer resistance in NMRs through different perspectives and directions, creating new knowledge that subsequently could be used for cancer prevention and delaying aging in humans. Thus, the purpose of this review is to summarize the recent knowledge on naked mole rats with a particular emphasis on the molecular mechanisms associated with their longevity and cancer resistance.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Chávez-Valencia, VeniceMaster in Health Sciences, Graduate Studies Division, Faculty of Biological and Medical Sciences "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo, Av. Rafael Carrillo without number, corner with Dr. Salvador González Herrejón, Bosque Cuauhtémoc, 58020, Morelia, Michoacán, Mexico; Nephrology Deparment, Regional General Hospital No. 1, Instituto Mexicano del Seguro Social, Av. Bosques de los Olivos No. 101, Comunidad La Goleta, 61301, Morelia, Michoacán, Mexico
(författare)
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Master in Health Sciences, Graduate Studies Division, Faculty of Biological and Medical Sciences "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo, Av. Rafael Carrillo without number, corner with Dr. Salvador González Herrejón, Bosque Cuauhtémoc, 58020, Morelia, Michoacán, MexicoMaster in Health Sciences, Graduate Studies Division, Faculty of Biological and Medical Sciences "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo, Av. Rafael Carrillo without number, corner with Dr. Salvador González Herrejón, Bosque Cuauhtémoc, 58020, Morelia, Michoacán, Mexico; Nephrology Deparment, Regional General Hospital No. 1, Instituto Mexicano del Seguro Social, Av. Bosques de los Olivos No. 101, Comunidad La Goleta, 61301, Morelia, Michoacán, Mexico
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Mechanisms of Ageing and Development: Elsevier BV164, s. 76-810047-63741872-6216
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