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The hidden structur...
The hidden structural variability in avian genomes
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- Peona, Valentina (författare)
- Uppsala universitet,Systematisk biologi,Science for Life Laboratory, SciLifeLab
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- Blom, Mozes P. K. (författare)
- Museum für Naturkunde, Leibniz Institut für Evolutions- und Biodiversitätsforschung, Berlin, Germany
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- Frankl-Vilches, Carolina (författare)
- Department of Behavioral Neurobiology, Max Planck Institute for Ornithology, 82319 Seewiesen, Germany
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- Milá, Borja (författare)
- Department of Biodiversity and Evolutionary Biology, National Museum of Natural Sciences, Spanish National Research Council (CSIC), Madrid, Spain
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- Ashari, Hidayat (författare)
- Museum Zoologicum Bogoriense, Indonesian Institute of Sciences (LIPI), Cibinong, Indonesia
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- Thébaud, Christophe (författare)
- UMR 5174 EDB CNRS, Université Paul Sabatier, IRD, Toulouse, France
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- Benz, Brett W. (författare)
- Museum of Zoology and Department of Ecology and Evolutionary Biology, University of Michigan
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- Christidis, Les (författare)
- School of Environment, Science and Engineering, Southern Cross University, Coffs Harbour, NSW Australia 2450
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- Gahr, Manfred (författare)
- Department of Behavioral Neurobiology, Max Planck Institute for Ornithology, 82319 Seewiesen, Germany
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- Irestedt, Martin (författare)
- Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden
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- Suh, Alexander (författare)
- Uppsala universitet,Science for Life Laboratory, SciLifeLab,Systematisk biologi,University of East Anglia
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(creator_code:org_t)
- Engelska.
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- Structural variants (SVs) are DNA mutations that can have relevant effects at the micro- and macro-evolutionary scales. The detection of SVs is largely limited by the type and quality of sequencing technologies adopted, therefore genetic variability linked to SVs may remain undiscovered especially in complex repetitive regions. In this study, we used a combination of long-read and linked-read genome assemblies to explore the occurrence of insertions and deletions across the chromosomes of 14 species birds-of-paradise and two species of estrildid finches. The species sampling encompasses all genera of birds-of-paradise, allowing comparisons between individuals of the same species, genus, and family. Interestingly, we found the highest densities of SVs to be located on the microchromosomes and on the female-specific W chromosome. Genome assemblies of multiple individuals from the same species allowed us to compare the levels of genetic variability linked to SVs and single nucleotide polymorphisms (SNPs) on the W and other chromosomes. Our results demonstrate that the avian W chromosome harbours more genetic variability than previously thought and that its structure is shaped by the continuous accumulation and turnover of transposable element insertions, especially endogenous retroviruses.
Ämnesord
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Nyckelord
- sex chromosome
- avian genomics
- deletion
- insertion
- structural variant
- satellite DNA
- transposable element
- endogenous retrovirus
- solo LTR
- full-length LTR
Publikations- och innehållstyp
- vet (ämneskategori)
- ovr (ämneskategori)
- Av författaren/redakt...
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Peona, Valentina
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Blom, Mozes P. K ...
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Frankl-Vilches, ...
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Milá, Borja
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Ashari, Hidayat
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Thébaud, Christo ...
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visa fler...
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Benz, Brett W.
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Christidis, Les
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Gahr, Manfred
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Irestedt, Martin
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Suh, Alexander
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visa färre...
- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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och Evolutionsbiolog ...
- Av lärosätet
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Uppsala universitet